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Dopaminergic Positron Emission Tomography Imaging in the Alpha‐Synuclein Preformed Fibril Model Reveals Similarities to Early Parkinson's Disease
BACKGROUND: Positron emission tomography (PET) imaging in early Parkinson's disease (PD) subjects reveals that increased dopamine (DA) turnover and reduced dopamine transporter (DAT) density precede decreases in DA synthesis and storage. The rat α‐synuclein preformed fibril (α‐syn PFF) model pr...
Autores principales: | Sossi, Vesna, Patterson, Joseph R., McCormick, Siobhan, Kemp, Christopher J., Miller, Kathryn M., Stoll, Anna C., Kuhn, Nathan, Kubik, Michael, Kochmanski, Joseph, Luk, Kelvin C., Sortwell, Caryl E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391270/ https://www.ncbi.nlm.nih.gov/pubmed/35524682 http://dx.doi.org/10.1002/mds.29051 |
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