Vasculogenesis in kidney organoids upon transplantation

Human induced pluripotent stem cell-derived kidney organoids have potential for disease modeling and to be developed into clinically transplantable auxiliary tissue. However, they lack a functional vasculature, and the sparse endogenous endothelial cells (ECs) are lost upon prolonged culture in vitr...

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Detalles Bibliográficos
Autores principales: Koning, Marije, Dumas, Sébastien J., Avramut, M. Cristina, Koning, Roman I., Meta, Elda, Lievers, Ellen, Wiersma, Loes E., Borri, Mila, Liang, Xue, Xie, Lin, Liu, Ping, Chen, Fang, Lin, Lin, Luo, Yonglun, Mulder, Jaap, Spijker, H. Siebe, Jaffredo, Thierry, van den Berg, Bernard M., Carmeliet, Peter, van den Berg, Cathelijne W., Rabelink, Ton J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391397/
https://www.ncbi.nlm.nih.gov/pubmed/35986027
http://dx.doi.org/10.1038/s41536-022-00237-4

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