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Human liver organoids for disease modeling of fibrolamellar carcinoma
Fibrolamellar carcinoma (FLC) is a rare, often lethal, liver cancer affecting adolescents and young adults, for which there are no approved therapeutics. The development of therapeutics is hampered by a lack of in vitro models. Organoids have shown utility as a model system for studying many disease...
Autores principales: | Narayan, Nicole J.C., Requena, David, Lalazar, Gadi, Ramos-Espiritu, Lavoisier, Ng, Denise, Levin, Solomon, Shebl, Bassem, Wang, Ruisi, Hammond, William J., Saltsman, James A., Gehart, Helmuth, Torbenson, Michael S., Clevers, Hans, LaQuaglia, Michael P., Simon, Sanford M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391427/ https://www.ncbi.nlm.nih.gov/pubmed/35803261 http://dx.doi.org/10.1016/j.stemcr.2022.06.003 |
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