Mettl14-driven senescence-associated secretory phenotype facilitates somatic cell reprogramming

The METTL3-METTL14 complex, the “writer” of N(6)-methyladenosine (m(6)A), plays an important role in many biological processes. Previous studies have shown that Mettl3 overexpression can increase the level of m(6)A and promote somatic cell reprogramming. Here, we demonstrate that Mettl14, another co...

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Detalles Bibliográficos
Autores principales: Xi, Chenxiang, Sun, Jiatong, Xu, Xiaocui, Wu, You, Kou, Xiaochen, Zhao, Yanhong, Shen, Jiacheng, Dong, Yu, Chen, Kang, Su, Zhongqu, Liu, Dan, Ye, Wen, Liu, Yingdong, Zhang, Ran, Xu, Yiliang, Wang, Hong, Hao, Lujiang, Wu, Li, Gao, Shaorong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391510/
https://www.ncbi.nlm.nih.gov/pubmed/35947961
http://dx.doi.org/10.1016/j.stemcr.2022.06.012

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