Elevated Anion Gap Metabolic Acidosis With High Osmolar Gap and Increased Serum Acetone Level: A Case Report

Acetone poisoning, although not very common, can present with varied signs and symptoms. High acetone levels in serum can be due to exogenous exposure or endogenous production of acetone. Unlike certain alcohol toxicities, acetone does not cause high anion gap metabolic acidosis. A 69-year-old male...

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Detalles Bibliográficos
Autores principales: Basuli, Debargha, Roy, Sasmit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Emergency Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391567/
https://www.ncbi.nlm.nih.gov/pubmed/36000112
http://dx.doi.org/10.7759/cureus.27085
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author Basuli, Debargha
Roy, Sasmit
author_facet Basuli, Debargha
Roy, Sasmit
author_sort Basuli, Debargha
collection PubMed
description Acetone poisoning, although not very common, can present with varied signs and symptoms. High acetone levels in serum can be due to exogenous exposure or endogenous production of acetone. Unlike certain alcohol toxicities, acetone does not cause high anion gap metabolic acidosis. A 69-year-old male presented to our service with shock and acute encephalopathy and required intensive care support. Initial laboratory investigation showed high anion gap metabolic acidosis with high osmolar gap. Serum acetone level was elevated. Clinicians need to be aware of how to elucidate such metabolic disturbances and associated toxicities.
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spelling pubmed-93915672022-08-22 Elevated Anion Gap Metabolic Acidosis With High Osmolar Gap and Increased Serum Acetone Level: A Case Report Basuli, Debargha Roy, Sasmit Cureus Emergency Medicine Acetone poisoning, although not very common, can present with varied signs and symptoms. High acetone levels in serum can be due to exogenous exposure or endogenous production of acetone. Unlike certain alcohol toxicities, acetone does not cause high anion gap metabolic acidosis. A 69-year-old male presented to our service with shock and acute encephalopathy and required intensive care support. Initial laboratory investigation showed high anion gap metabolic acidosis with high osmolar gap. Serum acetone level was elevated. Clinicians need to be aware of how to elucidate such metabolic disturbances and associated toxicities. Cureus 2022-07-20 /pmc/articles/PMC9391567/ /pubmed/36000112 http://dx.doi.org/10.7759/cureus.27085 Text en Copyright © 2022, Basuli et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Emergency Medicine
Basuli, Debargha
Roy, Sasmit
Elevated Anion Gap Metabolic Acidosis With High Osmolar Gap and Increased Serum Acetone Level: A Case Report
title Elevated Anion Gap Metabolic Acidosis With High Osmolar Gap and Increased Serum Acetone Level: A Case Report
title_full Elevated Anion Gap Metabolic Acidosis With High Osmolar Gap and Increased Serum Acetone Level: A Case Report
title_fullStr Elevated Anion Gap Metabolic Acidosis With High Osmolar Gap and Increased Serum Acetone Level: A Case Report
title_full_unstemmed Elevated Anion Gap Metabolic Acidosis With High Osmolar Gap and Increased Serum Acetone Level: A Case Report
title_short Elevated Anion Gap Metabolic Acidosis With High Osmolar Gap and Increased Serum Acetone Level: A Case Report
title_sort elevated anion gap metabolic acidosis with high osmolar gap and increased serum acetone level: a case report
topic Emergency Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391567/
https://www.ncbi.nlm.nih.gov/pubmed/36000112
http://dx.doi.org/10.7759/cureus.27085
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