Rituximab-Induced Interstitial Lung Disease: A Stitch in Time Saved Nine

A 59-year-old male was initially diagnosed with pemphigus Vulgaris and received rituximab after a suboptimal clinical response with low-dose steroids and cyclophosphamide. Shortly after the third dose, he had acute interstitial pneumonia which was attributed to rituximab as there were no signs of an...

Descripción completa

Detalles Bibliográficos
Autores principales: Tej, Sai, Undrajavarapu, Asha, Kadian, Kirti, Khurana, Alkesh, Goyal, Abhishek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Emergency Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391763/
https://www.ncbi.nlm.nih.gov/pubmed/36000124
http://dx.doi.org/10.7759/cureus.27088
Descripción
Sumario:A 59-year-old male was initially diagnosed with pemphigus Vulgaris and received rituximab after a suboptimal clinical response with low-dose steroids and cyclophosphamide. Shortly after the third dose, he had acute interstitial pneumonia which was attributed to rituximab as there were no signs of any infective etiology after a detailed workup. He was put on mechanical ventilation but the dramatic response to pulse steroids helped the patient in early extubation and a favorable outcome.

Ejemplares similares