Rituximab-Induced Interstitial Lung Disease: A Stitch in Time Saved Nine

A 59-year-old male was initially diagnosed with pemphigus Vulgaris and received rituximab after a suboptimal clinical response with low-dose steroids and cyclophosphamide. Shortly after the third dose, he had acute interstitial pneumonia which was attributed to rituximab as there were no signs of an...

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Autores principales: Tej, Sai, Undrajavarapu, Asha, Kadian, Kirti, Khurana, Alkesh, Goyal, Abhishek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Emergency Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391763/
https://www.ncbi.nlm.nih.gov/pubmed/36000124
http://dx.doi.org/10.7759/cureus.27088
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author Tej, Sai
Undrajavarapu, Asha
Kadian, Kirti
Khurana, Alkesh
Goyal, Abhishek
author_facet Tej, Sai
Undrajavarapu, Asha
Kadian, Kirti
Khurana, Alkesh
Goyal, Abhishek
author_sort Tej, Sai
collection PubMed
description A 59-year-old male was initially diagnosed with pemphigus Vulgaris and received rituximab after a suboptimal clinical response with low-dose steroids and cyclophosphamide. Shortly after the third dose, he had acute interstitial pneumonia which was attributed to rituximab as there were no signs of any infective etiology after a detailed workup. He was put on mechanical ventilation but the dramatic response to pulse steroids helped the patient in early extubation and a favorable outcome.
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spelling pubmed-93917632022-08-22 Rituximab-Induced Interstitial Lung Disease: A Stitch in Time Saved Nine Tej, Sai Undrajavarapu, Asha Kadian, Kirti Khurana, Alkesh Goyal, Abhishek Cureus Emergency Medicine A 59-year-old male was initially diagnosed with pemphigus Vulgaris and received rituximab after a suboptimal clinical response with low-dose steroids and cyclophosphamide. Shortly after the third dose, he had acute interstitial pneumonia which was attributed to rituximab as there were no signs of any infective etiology after a detailed workup. He was put on mechanical ventilation but the dramatic response to pulse steroids helped the patient in early extubation and a favorable outcome. Cureus 2022-07-20 /pmc/articles/PMC9391763/ /pubmed/36000124 http://dx.doi.org/10.7759/cureus.27088 Text en Copyright © 2022, Tej et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Emergency Medicine
Tej, Sai
Undrajavarapu, Asha
Kadian, Kirti
Khurana, Alkesh
Goyal, Abhishek
Rituximab-Induced Interstitial Lung Disease: A Stitch in Time Saved Nine
title Rituximab-Induced Interstitial Lung Disease: A Stitch in Time Saved Nine
title_full Rituximab-Induced Interstitial Lung Disease: A Stitch in Time Saved Nine
title_fullStr Rituximab-Induced Interstitial Lung Disease: A Stitch in Time Saved Nine
title_full_unstemmed Rituximab-Induced Interstitial Lung Disease: A Stitch in Time Saved Nine
title_short Rituximab-Induced Interstitial Lung Disease: A Stitch in Time Saved Nine
title_sort rituximab-induced interstitial lung disease: a stitch in time saved nine
topic Emergency Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391763/
https://www.ncbi.nlm.nih.gov/pubmed/36000124
http://dx.doi.org/10.7759/cureus.27088
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AT khuranaalkesh rituximabinducedinterstitiallungdiseaseastitchintimesavednine
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