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SCONCE2: jointly inferring single cell copy number profiles and tumor evolutionary distances

BACKGROUND: Single cell whole genome tumor sequencing can yield novel insights into the evolutionary history of somatic copy number alterations. Existing single cell copy number calling methods do not explicitly model the shared evolutionary process of multiple cells, and generally analyze cells ind...

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Detalles Bibliográficos
Autores principales: Hui, Sandra, Nielsen, Rasmus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392257/
https://www.ncbi.nlm.nih.gov/pubmed/35986254
http://dx.doi.org/10.1186/s12859-022-04890-w

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