Epstein-Barr viral product-containing exosomes promote fibrosis and nasopharyngeal carcinoma progression through activation of YAP1/FAPα signaling in fibroblasts

BACKGROUND: The progression of nasopharyngeal carcinoma (NPC) is profoundly affected by Epstein-Barr virus (EBV) infection. However, the role of EBV in the intercommunication between NPC and surrounding stromal cells has yet to be explored. METHODS: NPC biopsies were obtained for immunohistochemical...

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Detalles Bibliográficos
Autores principales: Lee, Po-Ju, Sui, Yun-Hua, Liu, Tzu-Tung, Tsang, Ngan-Ming, Huang, Chen-Han, Lin, Ting-Yi, Chang, Kai-Ping, Liu, Shu-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392321/
https://www.ncbi.nlm.nih.gov/pubmed/35986369
http://dx.doi.org/10.1186/s13046-022-02456-5

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