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iPSCs derived from insulin resistant offspring of type 2 diabetic patients show increased oxidative stress and lactate secretion

BACKGROUND: The genetic factors associated with insulin resistance (IR) are not well understood. Clinical studies on first-degree relatives of type 2 diabetic (T2D) patients, which have the highest genetic predisposition to T2D, have given insights into the role of IR in T2D pathogenesis. Induced pl...

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Detalles Bibliográficos
Autores principales:	Memon, Bushra, Elsayed, Ahmed K., Bettahi, Ilham, Suleiman, Noor, Younis, Ihab, Wehedy, Eman, Abou-Samra, Abdul Badi, Abdelalim, Essam M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392338/ https://www.ncbi.nlm.nih.gov/pubmed/35987697 http://dx.doi.org/10.1186/s13287-022-03123-4

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