Cargando…
Intraoperative quantitative assessment of parathyroid blood flow during total thyroidectomy using indocyanine green fluorescence imaging ‐ surgical strategies for preserving the function of parathyroid glands
OBJECTIVE: We investigated the factors affecting postoperative parathyroid gland (PTG) function and devised an objective index to predict the postoperative PTG function during total thyroidectomy. METHOD: This was a retrospective clinical review of 21 consecutive patients who were diagnosed with pap...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392388/ https://www.ncbi.nlm.nih.gov/pubmed/36000062 http://dx.doi.org/10.1002/lio2.868 |
_version_ | 1784771050788093952 |
---|---|
author | Iritani, Keisuke Teshima, Masanori Shimoda, Hikari Shinomiya, Hirotaka Otsuki, Naoki Nibu, Ken‐ichi |
author_facet | Iritani, Keisuke Teshima, Masanori Shimoda, Hikari Shinomiya, Hirotaka Otsuki, Naoki Nibu, Ken‐ichi |
author_sort | Iritani, Keisuke |
collection | PubMed |
description | OBJECTIVE: We investigated the factors affecting postoperative parathyroid gland (PTG) function and devised an objective index to predict the postoperative PTG function during total thyroidectomy. METHOD: This was a retrospective clinical review of 21 consecutive patients who were diagnosed with papillary thyroid carcinoma and underwent total thyroidectomy. The maximum intensity ratio (MIR) was determined as the maximum fluorescence intensity after ICG injection divided by the intensity before ICG injection. RESULTS: Postoperative hypoparathyroidism is significantly associated with simultaneous central neck dissection (CND) and lateral neck dissection (LND) (p = .032). The Spearman correlation test showed a moderate correlation between the MIR and iPTH levels (p = .0047). The optimal MIR cutoff value for predicting postoperative hypoparathyroidism was 2.14 with area under the curve = 0.904 (sensitivity: 0.769 and specificity: 1.00). CONCLUSION: CND + LND was significantly associated with postoperative hypoparathyroidism. MIR was found useful in predicting the postoperative PTG function. LEVEL OF EVIDENCE: 3B. |
format | Online Article Text |
id | pubmed-9392388 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley & Sons, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-93923882022-08-22 Intraoperative quantitative assessment of parathyroid blood flow during total thyroidectomy using indocyanine green fluorescence imaging ‐ surgical strategies for preserving the function of parathyroid glands Iritani, Keisuke Teshima, Masanori Shimoda, Hikari Shinomiya, Hirotaka Otsuki, Naoki Nibu, Ken‐ichi Laryngoscope Investig Otolaryngol Thyroid, Parathyroid, and Endocrine OBJECTIVE: We investigated the factors affecting postoperative parathyroid gland (PTG) function and devised an objective index to predict the postoperative PTG function during total thyroidectomy. METHOD: This was a retrospective clinical review of 21 consecutive patients who were diagnosed with papillary thyroid carcinoma and underwent total thyroidectomy. The maximum intensity ratio (MIR) was determined as the maximum fluorescence intensity after ICG injection divided by the intensity before ICG injection. RESULTS: Postoperative hypoparathyroidism is significantly associated with simultaneous central neck dissection (CND) and lateral neck dissection (LND) (p = .032). The Spearman correlation test showed a moderate correlation between the MIR and iPTH levels (p = .0047). The optimal MIR cutoff value for predicting postoperative hypoparathyroidism was 2.14 with area under the curve = 0.904 (sensitivity: 0.769 and specificity: 1.00). CONCLUSION: CND + LND was significantly associated with postoperative hypoparathyroidism. MIR was found useful in predicting the postoperative PTG function. LEVEL OF EVIDENCE: 3B. John Wiley & Sons, Inc. 2022-07-18 /pmc/articles/PMC9392388/ /pubmed/36000062 http://dx.doi.org/10.1002/lio2.868 Text en © 2022 The Authors. Laryngoscope Investigative Otolaryngology published by Wiley Periodicals LLC. on behalf of The Triological Society. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Thyroid, Parathyroid, and Endocrine Iritani, Keisuke Teshima, Masanori Shimoda, Hikari Shinomiya, Hirotaka Otsuki, Naoki Nibu, Ken‐ichi Intraoperative quantitative assessment of parathyroid blood flow during total thyroidectomy using indocyanine green fluorescence imaging ‐ surgical strategies for preserving the function of parathyroid glands |
title | Intraoperative quantitative assessment of parathyroid blood flow during total thyroidectomy using indocyanine green fluorescence imaging ‐ surgical strategies for preserving the function of parathyroid glands |
title_full | Intraoperative quantitative assessment of parathyroid blood flow during total thyroidectomy using indocyanine green fluorescence imaging ‐ surgical strategies for preserving the function of parathyroid glands |
title_fullStr | Intraoperative quantitative assessment of parathyroid blood flow during total thyroidectomy using indocyanine green fluorescence imaging ‐ surgical strategies for preserving the function of parathyroid glands |
title_full_unstemmed | Intraoperative quantitative assessment of parathyroid blood flow during total thyroidectomy using indocyanine green fluorescence imaging ‐ surgical strategies for preserving the function of parathyroid glands |
title_short | Intraoperative quantitative assessment of parathyroid blood flow during total thyroidectomy using indocyanine green fluorescence imaging ‐ surgical strategies for preserving the function of parathyroid glands |
title_sort | intraoperative quantitative assessment of parathyroid blood flow during total thyroidectomy using indocyanine green fluorescence imaging ‐ surgical strategies for preserving the function of parathyroid glands |
topic | Thyroid, Parathyroid, and Endocrine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392388/ https://www.ncbi.nlm.nih.gov/pubmed/36000062 http://dx.doi.org/10.1002/lio2.868 |
work_keys_str_mv | AT iritanikeisuke intraoperativequantitativeassessmentofparathyroidbloodflowduringtotalthyroidectomyusingindocyaninegreenfluorescenceimagingsurgicalstrategiesforpreservingthefunctionofparathyroidglands AT teshimamasanori intraoperativequantitativeassessmentofparathyroidbloodflowduringtotalthyroidectomyusingindocyaninegreenfluorescenceimagingsurgicalstrategiesforpreservingthefunctionofparathyroidglands AT shimodahikari intraoperativequantitativeassessmentofparathyroidbloodflowduringtotalthyroidectomyusingindocyaninegreenfluorescenceimagingsurgicalstrategiesforpreservingthefunctionofparathyroidglands AT shinomiyahirotaka intraoperativequantitativeassessmentofparathyroidbloodflowduringtotalthyroidectomyusingindocyaninegreenfluorescenceimagingsurgicalstrategiesforpreservingthefunctionofparathyroidglands AT otsukinaoki intraoperativequantitativeassessmentofparathyroidbloodflowduringtotalthyroidectomyusingindocyaninegreenfluorescenceimagingsurgicalstrategiesforpreservingthefunctionofparathyroidglands AT nibukenichi intraoperativequantitativeassessmentofparathyroidbloodflowduringtotalthyroidectomyusingindocyaninegreenfluorescenceimagingsurgicalstrategiesforpreservingthefunctionofparathyroidglands |