The blunted vascular endothelial growth factor-A (VEGF-A) response to high-altitude hypoxia and genetic variants in the promoter region of the VEGFA gene in Sherpa highlanders

BACKGROUND: Sherpa highlanders demonstrate extraordinary tolerance to hypoxia at high altitudes, which may be achieved by mechanisms promoting microcirculatory blood flow and capillary density at high altitudes for restoring oxygen supply to tissues. Vascular endothelial growth factors (VEGFs) are i...

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Detalles Bibliográficos
Autores principales: Droma, Yunden, Hanaoka, Masayuki, Kinjo, Takumi, Kobayashi, Nobumitsu, Yasuo, Masanori, Kitaguchi, Yoshiaki, Ota, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392454/
https://www.ncbi.nlm.nih.gov/pubmed/35996666
http://dx.doi.org/10.7717/peerj.13893

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