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Geriatric Nutritional Risk Index is related to the risk of stroke‐associated pneumonia

BACKGROUND: Stroke‐associated pneumonia (SAP) occurs frequently after a stroke. Geriatric Nutritional Risk Index (GNRI) is a valuable indicator of elderly individuals’ nutritional status. This research was designed to obtain insight into the link between GNRI and SAP. METHODS: Patients with acute is...

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Autores principales: Dai, Caijun, Yan, Dan, Xu, Minjie, Huang, Qiqi, Ren, Wenwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392546/
https://www.ncbi.nlm.nih.gov/pubmed/35849734
http://dx.doi.org/10.1002/brb3.2718
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author Dai, Caijun
Yan, Dan
Xu, Minjie
Huang, Qiqi
Ren, Wenwei
author_facet Dai, Caijun
Yan, Dan
Xu, Minjie
Huang, Qiqi
Ren, Wenwei
author_sort Dai, Caijun
collection PubMed
description BACKGROUND: Stroke‐associated pneumonia (SAP) occurs frequently after a stroke. Geriatric Nutritional Risk Index (GNRI) is a valuable indicator of elderly individuals’ nutritional status. This research was designed to obtain insight into the link between GNRI and SAP. METHODS: Patients with acute ischemic stroke (AIS) were categorized into the SAP and non‐SAP groups. GNRI scores were divided into four layers: Q1, GNRI < 82; Q2, 82≤ GNRI < 92; Q3, 92≤ GNRI ≤98; Q4, GNRI > 98. To identify the independent risk and protective factors of developing SAP, logistic regression analyses were conducted. Additionally, we utilized the restricted cubic spline (RCS) analysis to test the effect of GNRI on the SAP risk. RESULTS: The SAP group showed lower GNRI scores than the non‐SAP group (96.88 ± 9.36 vs. 100.88 ± 8.25, p  <  0.001). According to the logistic regression model, the Q1 and Q2 layers showed a higher risk of SAP than the Q3 layer, while the Q4 layer showed a lower SAP risk (all p < 0.05). Besides, the RCS model found that the risk of SAP dropped dramatically as GNRI scores increased, which got stable when the GNRI score was more significant than 100. CONCLUSION: Lower GNRI scores were linked to a higher prevalence of SAP. In clinical practice, GNRI showed predictive value for SAP, which could be helpful in early SAP intervention and therapy.
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spelling pubmed-93925462022-08-24 Geriatric Nutritional Risk Index is related to the risk of stroke‐associated pneumonia Dai, Caijun Yan, Dan Xu, Minjie Huang, Qiqi Ren, Wenwei Brain Behav Original Articles BACKGROUND: Stroke‐associated pneumonia (SAP) occurs frequently after a stroke. Geriatric Nutritional Risk Index (GNRI) is a valuable indicator of elderly individuals’ nutritional status. This research was designed to obtain insight into the link between GNRI and SAP. METHODS: Patients with acute ischemic stroke (AIS) were categorized into the SAP and non‐SAP groups. GNRI scores were divided into four layers: Q1, GNRI < 82; Q2, 82≤ GNRI < 92; Q3, 92≤ GNRI ≤98; Q4, GNRI > 98. To identify the independent risk and protective factors of developing SAP, logistic regression analyses were conducted. Additionally, we utilized the restricted cubic spline (RCS) analysis to test the effect of GNRI on the SAP risk. RESULTS: The SAP group showed lower GNRI scores than the non‐SAP group (96.88 ± 9.36 vs. 100.88 ± 8.25, p  <  0.001). According to the logistic regression model, the Q1 and Q2 layers showed a higher risk of SAP than the Q3 layer, while the Q4 layer showed a lower SAP risk (all p < 0.05). Besides, the RCS model found that the risk of SAP dropped dramatically as GNRI scores increased, which got stable when the GNRI score was more significant than 100. CONCLUSION: Lower GNRI scores were linked to a higher prevalence of SAP. In clinical practice, GNRI showed predictive value for SAP, which could be helpful in early SAP intervention and therapy. John Wiley and Sons Inc. 2022-07-18 /pmc/articles/PMC9392546/ /pubmed/35849734 http://dx.doi.org/10.1002/brb3.2718 Text en © 2022 The Authors. Brain and Behavior published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Dai, Caijun
Yan, Dan
Xu, Minjie
Huang, Qiqi
Ren, Wenwei
Geriatric Nutritional Risk Index is related to the risk of stroke‐associated pneumonia
title Geriatric Nutritional Risk Index is related to the risk of stroke‐associated pneumonia
title_full Geriatric Nutritional Risk Index is related to the risk of stroke‐associated pneumonia
title_fullStr Geriatric Nutritional Risk Index is related to the risk of stroke‐associated pneumonia
title_full_unstemmed Geriatric Nutritional Risk Index is related to the risk of stroke‐associated pneumonia
title_short Geriatric Nutritional Risk Index is related to the risk of stroke‐associated pneumonia
title_sort geriatric nutritional risk index is related to the risk of stroke‐associated pneumonia
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392546/
https://www.ncbi.nlm.nih.gov/pubmed/35849734
http://dx.doi.org/10.1002/brb3.2718
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