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A comparative study of the toxic effect of ZIF-8 and ZIF-L on the colonization and decomposition of shaded outdoor mice carrions by arthropods

Metal–organic frameworks (MOFs) are promising materials for several applications. Thus, they have been intensively reported and commercialized by several international companies. However, little is known about the fate and risk of MOFs to living organisms. Here, the toxic effect of two Zinc (Zn)-bas...

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Autores principales: Abd El-Aziz, Fatma El-Zahraa A., Ebrahem, Noha Esmael, Abdelhamid, Hani Nasser
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392756/
https://www.ncbi.nlm.nih.gov/pubmed/35987914
http://dx.doi.org/10.1038/s41598-022-18322-5
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author Abd El-Aziz, Fatma El-Zahraa A.
Ebrahem, Noha Esmael
Abdelhamid, Hani Nasser
author_facet Abd El-Aziz, Fatma El-Zahraa A.
Ebrahem, Noha Esmael
Abdelhamid, Hani Nasser
author_sort Abd El-Aziz, Fatma El-Zahraa A.
collection PubMed
description Metal–organic frameworks (MOFs) are promising materials for several applications. Thus, they have been intensively reported and commercialized by several international companies. However, little is known about the fate and risk of MOFs to living organisms. Here, the toxic effect of two Zinc (Zn)-based MOFs; zeolitic imidazolate frameworks (ZIF-8) and leaf-like ZIF (ZIF-L), was tested to investigate the impact of the postmortem period of mice carrions and arthropods which found in decomposing carrions. The data analysis revealed an increase in zinc content over time. Toxicology in forensics studies biological materials for the presence of poisons, such as pharmaceuticals. The toxicology report can provide important details about the types of chemicals present in a person and whether the amount of those substances is in line with a therapeutic dose or exceeds a dangerous level. These findings conclude the possible fate and impact after mortality. This study presents the first study of the toxic effect of ZIFs materials using mice carrions and arthropods (Sarcophaga sp. Larvae) via morphological and microscopic studies compared with control, providing important biological information could aid in the environmental impact of the toxic level of MOF materials.
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spelling pubmed-93927562022-08-22 A comparative study of the toxic effect of ZIF-8 and ZIF-L on the colonization and decomposition of shaded outdoor mice carrions by arthropods Abd El-Aziz, Fatma El-Zahraa A. Ebrahem, Noha Esmael Abdelhamid, Hani Nasser Sci Rep Article Metal–organic frameworks (MOFs) are promising materials for several applications. Thus, they have been intensively reported and commercialized by several international companies. However, little is known about the fate and risk of MOFs to living organisms. Here, the toxic effect of two Zinc (Zn)-based MOFs; zeolitic imidazolate frameworks (ZIF-8) and leaf-like ZIF (ZIF-L), was tested to investigate the impact of the postmortem period of mice carrions and arthropods which found in decomposing carrions. The data analysis revealed an increase in zinc content over time. Toxicology in forensics studies biological materials for the presence of poisons, such as pharmaceuticals. The toxicology report can provide important details about the types of chemicals present in a person and whether the amount of those substances is in line with a therapeutic dose or exceeds a dangerous level. These findings conclude the possible fate and impact after mortality. This study presents the first study of the toxic effect of ZIFs materials using mice carrions and arthropods (Sarcophaga sp. Larvae) via morphological and microscopic studies compared with control, providing important biological information could aid in the environmental impact of the toxic level of MOF materials. Nature Publishing Group UK 2022-08-20 /pmc/articles/PMC9392756/ /pubmed/35987914 http://dx.doi.org/10.1038/s41598-022-18322-5 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Abd El-Aziz, Fatma El-Zahraa A.
Ebrahem, Noha Esmael
Abdelhamid, Hani Nasser
A comparative study of the toxic effect of ZIF-8 and ZIF-L on the colonization and decomposition of shaded outdoor mice carrions by arthropods
title A comparative study of the toxic effect of ZIF-8 and ZIF-L on the colonization and decomposition of shaded outdoor mice carrions by arthropods
title_full A comparative study of the toxic effect of ZIF-8 and ZIF-L on the colonization and decomposition of shaded outdoor mice carrions by arthropods
title_fullStr A comparative study of the toxic effect of ZIF-8 and ZIF-L on the colonization and decomposition of shaded outdoor mice carrions by arthropods
title_full_unstemmed A comparative study of the toxic effect of ZIF-8 and ZIF-L on the colonization and decomposition of shaded outdoor mice carrions by arthropods
title_short A comparative study of the toxic effect of ZIF-8 and ZIF-L on the colonization and decomposition of shaded outdoor mice carrions by arthropods
title_sort comparative study of the toxic effect of zif-8 and zif-l on the colonization and decomposition of shaded outdoor mice carrions by arthropods
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392756/
https://www.ncbi.nlm.nih.gov/pubmed/35987914
http://dx.doi.org/10.1038/s41598-022-18322-5
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