Cargando…

MYBL1 induces transcriptional activation of ANGPT2 to promote tumor angiogenesis and confer sorafenib resistance in human hepatocellular carcinoma

Angiogenesis is considered as an important process in tumor growth, metastasis of hepatocellular carcinoma (HCC) and associated with cancer progression, suggesting that an important research and development field of clinical molecular targeted drugs for HCC. However, the molecular mechanisms underly...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Jinrong, Wu, Yongqi, Yu, Yijian, Li, Yan, Shen, Jianfei, Zhang, Rongxin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392790/ https://www.ncbi.nlm.nih.gov/pubmed/35987690 http://dx.doi.org/10.1038/s41419-022-05180-2

Ejemplares similares

Targeting TRIM54/Axin1/β-Catenin Axis Prohibits Proliferation and Metastasis in Hepatocellular Carcinoma
por: Zhu, Jinrong, et al.
Publicado: (2021)

ANGPT2 and NOS3 Polymorphisms and Clinical Outcome in Advanced Hepatocellular Carcinoma Patients Receiving Sorafenib
por: Marisi, Giorgia, et al.
Publicado: (2019)

Inactivation of Transcriptional Repressor Capicua Confers Sorafenib Resistance in Human Hepatocellular Carcinoma
por: Hashiba, Tomomi, et al.
Publicado: (2020)

MYBL2 regulates de novo purine synthesis by transcriptionally activating IMPDH1 in hepatocellular carcinoma cells
por: Zhao, Jun-Zhang, et al.
Publicado: (2022)

Overexpression of MYBL2 predicts poor prognosis and promotes oncogenesis in endometrial carcinoma
por: Le, Lulu, et al.
Publicado: (2021)

The Roles Of Angiogenesis And Cancer Stem Cells In Sorafenib Drug Resistance In Hepatocellular Carcinoma
por: Cheng, Chiung-Chi, et al.
Publicado: (2019)

circ-MYBL2 Serves As A Sponge For miR-361-3p Promoting Cervical Cancer Cells Proliferation And Invasion
por: Wang, Jinrong, et al.
Publicado: (2019)

Exosomal miR-3682-3p Suppresses Angiogenesis by Targeting ANGPT1 via the RAS-MEK1/2-ERK1/2 Pathway in Hepatocellular Carcinoma
por: Dong, Shuang-Shuang, et al.
Publicado: (2021)

Immune-related gene ANGPT1 is an adverse biomarker for endometrial carcinoma
por: Nong, Binbin, et al.
Publicado: (2021)

Silencing activating transcription factor 2 promotes the anticancer activity of sorafenib in hepatocellular carcinoma cells
por: Luo, Lifang, et al.
Publicado: (2018)

Phosphoprotein enriched in diabetes (PED/PEA15) promotes migration in hepatocellular carcinoma and confers resistance to sorafenib
por: Quintavalle, Cristina, et al.
Publicado: (2017)

Dual targeting of ANGPT1 and TGFBR2 genes by miR-204 controls angiogenesis in breast cancer
por: Flores-Pérez, Ali, et al.
Publicado: (2016)

Atorvastatin pleiotropically decreases intraplaque angiogenesis and intraplaque haemorrhage by inhibiting ANGPT2 release and VE-Cadherin internalization
por: Baganha, Fabiana, et al.
Publicado: (2021)

Co-option of Liver Vessels and Not Sprouting Angiogenesis Drives Acquired Sorafenib Resistance in Hepatocellular Carcinoma
por: Kuczynski, Elizabeth A., et al.
Publicado: (2016)

MiR-29a Curbs Hepatocellular Carcinoma Incidence via Targeting of HIF-1α and ANGPT2
por: Huang, Ying-Hsien, et al.
Publicado: (2022)

Sorafenib Monotherapy Versus Sorafenib Combined with Regional Therapies for Hepatocellular Carcinoma Patients with Pulmonary Oligometastases: A Propensity Score-matched Analysis
por: Chen, Jinbin, et al.
Publicado: (2018)

Clonal Dominance With Retroviral Vector Insertions Near the ANGPT1 and ANGPT2 Genes in a Human Xenotransplant Mouse Model
por: Haemmerle, Reinhard, et al.
Publicado: (2014)

Exosomal lncRNA-H19 promotes osteogenesis and angiogenesis through mediating Angpt1/Tie2-NO signaling in CBS-heterozygous mice
por: Behera, Jyotirmaya, et al.
Publicado: (2021)

Distinct Roles of VEGFA and ANGPT2 in Lung Adenocarcinoma and Squamous Cell Carcinoma
por: Qin, Shuang, et al.
Publicado: (2020)

Ivermectin synergizes sorafenib in hepatocellular carcinoma via targeting multiple oncogenic pathways
por: Lu, Haofeng, et al.
Publicado: (2022)

A MYBL2 complex for RRM2 transactivation and the synthetic effect of MYBL2 knockdown with WEE1 inhibition against colorectal cancer
por: Liu, Qian, et al.
Publicado: (2021)

Characterizing and Targeting Genes Regulated by Transcription Factor MYBL2 in Lung Adenocarcinoma Cells
por: Lee, Yuri, et al.
Publicado: (2022)

Golgi phosphoprotein 3 promotes angiogenesis and sorafenib resistance in hepatocellular carcinoma via upregulating exosomal miR-494-3p
por: Gao, Ying, et al.
Publicado: (2022)

Sorafenib in the Treatment of Advanced Hepatocellular Carcinoma
por: Mousa, Ali Ben
Publicado: (2008)

Sorafenib for the treatment of unresectable hepatocellular carcinoma
por: Furuse, Junji
Publicado: (2008)

Sorafenib Effectiveness in Advanced Hepatocellular Carcinoma
por: Sanoff, Hanna K., et al.
Publicado: (2016)

Sorafenib inhibits tumor cell growth and angiogenesis in canine transitional cell carcinoma
por: YOKOTA, Shohei, et al.
Publicado: (2022)

YY1 Promotes Endothelial Cell-Dependent Tumor Angiogenesis in Hepatocellular Carcinoma by Transcriptionally Activating VEGFA
por: Yang, Wendong, et al.
Publicado: (2019)

Synergistic growth inhibition by sorafenib and vitamin K2 in human hepatocellular carcinoma cells
por: Zhang, Yafei, et al.
Publicado: (2012)

Bclaf1 promotes angiogenesis by regulating HIF-1α transcription in hepatocellular carcinoma
por: Wen, Ying, et al.
Publicado: (2018)

MYBL2 disrupts the Hippo-YAP pathway and confers castration resistance and metastatic potential in prostate cancer
por: Li, Qiji, et al.
Publicado: (2021)

Activation of UBEC2 by transcription factor MYBL2 affects DNA damage and promotes gastric cancer progression and cisplatin resistance
por: Long, Jiegen, et al.
Publicado: (2023)

Transcriptional repression of ANGPT1 by histone H3K9 demethylase KDM3B
por: Han, Arim, et al.
Publicado: (2015)

Sorafenib Rechallenge and Sorafenib after Lenvatinib Failure in a Patient with Hepatocellular Carcinoma
por: Ikeda, Atsuyuki, et al.
Publicado: (2021)

Sestrin 2 confers primary resistance to sorafenib by simultaneously activating AKT and AMPK in hepatocellular carcinoma
por: Dai, Jimin, et al.
Publicado: (2018)

PLEKHG5 is stabilized by HDAC2-related deacetylation and confers sorafenib resistance in hepatocellular carcinoma
por: Sha, Yu, et al.
Publicado: (2023)

Knockdown MTDH Inhibits Glioma Proliferation and Migration and Promotes Apoptosis by Downregulating MYBL2
por: Fu, Junqi, et al.
Publicado: (2022)

Tissue-specific epigenetics of atherosclerosis-related ANGPT and ANGPTL genes
por: Ehrlich, Kenneth C, et al.
Publicado: (2019)

Angpt2/Tie2 autostimulatory loop controls tumorigenesis
por: Karabid, Ninelia Minaskan, et al.
Publicado: (2022)

Genetic association of ANGPT2 with primary open-angle glaucoma
por: He, Jing Na, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_g6jm5affhn1rmcq2ccf1cd4qj7