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Genomic targets and selective inhibition of DNA methyltransferase isoforms

BACKGROUND: DNA methylation in the human genome is established and maintained by DNA methyltransferases (DNMTs). DNMT isoforms show differential expression by cell lineage and during development, but much remains to be elucidated about their shared and unique genomic targets. RESULTS: We examined ch...

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Detalles Bibliográficos
Autores principales: Sae-Lee, Chanachai, Barrow, Timothy M., Colicino, Elena, Choi, Si Ho, Rabanal-Ruiz, Yoana, Green, Daniel, Korolchuk, Viktor I., Mathers, John C., Byun, Hyang-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392947/
https://www.ncbi.nlm.nih.gov/pubmed/35987848
http://dx.doi.org/10.1186/s13148-022-01325-4