Cargando…

Genomic targets and selective inhibition of DNA methyltransferase isoforms

BACKGROUND: DNA methylation in the human genome is established and maintained by DNA methyltransferases (DNMTs). DNMT isoforms show differential expression by cell lineage and during development, but much remains to be elucidated about their shared and unique genomic targets. RESULTS: We examined ch...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sae-Lee, Chanachai, Barrow, Timothy M., Colicino, Elena, Choi, Si Ho, Rabanal-Ruiz, Yoana, Green, Daniel, Korolchuk, Viktor I., Mathers, John C., Byun, Hyang-Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392947/ https://www.ncbi.nlm.nih.gov/pubmed/35987848 http://dx.doi.org/10.1186/s13148-022-01325-4

Ejemplares similares

mTORC1 and Nutrient Homeostasis: The Central Role of the Lysosome
por: Rabanal-Ruiz, Yoana, et al.
Publicado: (2018)

DNA methylation patterns of LINE-1 and Alu for pre-symptomatic dementia in type 2 diabetes
por: Sae-Lee, Chanachai, et al.
Publicado: (2020)

mTORC1 as the main gateway to autophagy
por: Rabanal-Ruiz, Yoana, et al.
Publicado: (2017)

Identification of preferential target sites for human DNA methyltransferases
por: Choi, Si Ho, et al.
Publicado: (2011)

The Roles of Human DNA Methyltransferases and Their Isoforms in Shaping the Epigenome
por: Gujar, Hemant, et al.
Publicado: (2019)

Unique Role for a DNA Methyltransferase Isoform in Lung Cancer
por: Duymich, Christopher E., et al.
Publicado: (2015)

Effects of Air Pollution and Blood Mitochondrial DNA Methylation on Markers of Heart Rate Variability
por: Byun, Hyang‐Min, et al.
Publicado: (2016)

Comprehensive analysis of regulation of DNA methyltransferase isoforms in human breast tumors
por: Hegde, Mangala, et al.
Publicado: (2021)

Obesity as an effect modifier of the association between menstrual abnormalities and hypertension in young adult women: Results from Project ELEFANT
por: Xu, Hui, et al.
Publicado: (2018)

DNA methylation and DNA methyltransferases
por: Edwards, John R., et al.
Publicado: (2017)

DNA methyltransferase isoforms expression in the temporal lobe of epilepsy patients with a history of febrile seizures
por: de Nijs, Laurence, et al.
Publicado: (2019)

The Use of Coenzyme Q10 in Cardiovascular Diseases
por: Rabanal-Ruiz, Yoana, et al.
Publicado: (2021)

DNA Methyltransferase1 (DNMT1) Isoform3 methylates mitochondrial genome and modulates its biology
por: Saini, Sunil Kumar, et al.
Publicado: (2017)

Editorial: Environmental Genomics and Epigenomics: Response, Development and Disease
por: Li, Yanqiang, et al.
Publicado: (2021)

Persistent mTORC1 signaling in cell senescence results from defects in amino acid and growth factor sensing
por: Carroll, Bernadette, et al.
Publicado: (2017)

Analysis of retrotransposon subfamily DNA methylation reveals novel early epigenetic changes in chronic lymphocytic leukemia
por: Barrow, Timothy M., et al.
Publicado: (2020)

Platelet mitochondrial DNA methylation predicts future cardiovascular outcome in adults with overweight and obesity
por: Corsi, Sarah, et al.
Publicado: (2020)

mTORC1 activity is supported by spatial association with focal adhesions
por: Rabanal-Ruiz, Yoana, et al.
Publicado: (2021)

NDP52 acts as a redox sensor in PINK1/Parkin‐mediated mitophagy
por: Kataura, Tetsushi, et al.
Publicado: (2022)

The Protective Effect of Ubiquinone against the Amyloid Peptide in Endothelial Cells Is Isoprenoid Chain Length-Dependent
por: Frontiñán-Rubio, Javier, et al.
Publicado: (2021)

Dietary Flavones as Dual Inhibitors of DNA Methyltransferases and Histone Methyltransferases
por: Kanwal, Rajnee, et al.
Publicado: (2016)

Expression of DNA Methyltransferase 3B Isoforms Is Associated with DNA Satellite 2 Hypomethylation and Clinical Prognosis in Advanced High-Grade Serous Ovarian Carcinoma
por: Del Castillo Falconi, Victor M., et al.
Publicado: (2022)

Selective Inhibitors of Protein Methyltransferases
por: Kaniskan, H. Ümit, et al.
Publicado: (2014)

DNA methyltransferases and their roles in tumorigenesis
por: Zhang, Wu, et al.
Publicado: (2017)

DNA Methyltransferases in Depression: An Update
por: Duan, Zhenghao, et al.
Publicado: (2020)

Light‐Activation of DNA‐Methyltransferases
por: Wolffgramm, Jan, et al.
Publicado: (2021)

Correction: Dietary Flavones as Dual Inhibitors of DNA Methyltransferases and Histone Methyltransferases
por: Kanwal, Rajnee, et al.
Publicado: (2016)

Coordinate regulation of DNA methyltransferase expression during oogenesis
por: Lucifero, Diana, et al.
Publicado: (2007)

Kinetic Basis of the Bifunctionality of SsoII DNA Methyltransferase
por: Timofeyeva, Nadezhda A., et al.
Publicado: (2018)

ChREBP Regulates Itself and Metabolic Genes Implicated in Lipid Accumulation in β–Cell Line
por: Sae-Lee, Chanachai, et al.
Publicado: (2016)

Nutrient sensing, growth and senescence
por: Carroll, Bernadette, et al.
Publicado: (2018)

Dysregulation of mTORC1/autophagy axis in senescence
por: Carroll, Bernadette, et al.
Publicado: (2017)

The crosstalk of NAD, ROS and autophagy in cellular health and ageing
por: Sedlackova, Lucia, et al.
Publicado: (2020)

REBASE—restriction enzymes and DNA methyltransferases
por: Roberts, Richard J., et al.
Publicado: (2005)

Fidelity Index Determination of DNA Methyltransferases
por: Borgaro, Janine G., et al.
Publicado: (2013)

Regulation of neuronal survival by DNA methyltransferases
por: Symmank, Judit, et al.
Publicado: (2017)

Mechanisms of DNA Methyltransferase Recruitment in Mammals
por: Laisné, Marthe, et al.
Publicado: (2018)

Editorial—Role of DNA Methyltransferases in the Epigenome
por: Jeltsch, Albert, et al.
Publicado: (2019)

Heterodimeric DNA methyltransferases as a platform for creating designer zinc finger methyltransferases for targeted DNA methylation in cells
por: Meister, Glenna E., et al.
Publicado: (2010)

Expression of DNA Methyltransferases in Breast Cancer Patients and to Analyze the Effect of Natural Compounds on DNA Methyltransferases and Associated Proteins
por: Mirza, Sameer, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_vovkd5lhml3q1vjg0k63teiabn