IC(50): an unsuitable measure for large-sized prostate cancer spheroids in drug sensitivity evaluation

Preclinical models of tumors have the potential to become valuable tools for commercial drug research and development, and 3D culture systems are gaining traction in this area, particularly in prostate cancer (PCa) research. However, nearly all 3D drug design and screening assessments are based on 2...

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Detalles Bibliográficos
Autores principales: Xu, Yipeng, Pachnikova, Gabriela, Wang, He, Wu, Yaoyao, Przybilla, Dorothea, Schäfer, Reinhold, Chen, Zihao, Zhu, Shaoxing, Keilholz, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392968/
https://www.ncbi.nlm.nih.gov/pubmed/35694767
http://dx.doi.org/10.17305/bjbms.2022.7279

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