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A Rare Occurrence of an Extensive Sino-Nasal Solitary Fibrous Tumour

INTRODUCTION: Solitary fibrous tumours are uncommon in head and neck region, especially in the nasal cavities and paranasal sinuses, with most cases reported in the thoracic region in the pleura. It is often considered a borderline or low-grade malignant soft tissue tumour. Complete surgical resecti...

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Autores principales: Cheah, Pei Fen, Ali, Azman, Shanmuganathan, Jothi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392996/
https://www.ncbi.nlm.nih.gov/pubmed/36035651
http://dx.doi.org/10.22038/IJORL.2022.58819.3032
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author Cheah, Pei Fen
Ali, Azman
Shanmuganathan, Jothi
author_facet Cheah, Pei Fen
Ali, Azman
Shanmuganathan, Jothi
author_sort Cheah, Pei Fen
collection PubMed
description INTRODUCTION: Solitary fibrous tumours are uncommon in head and neck region, especially in the nasal cavities and paranasal sinuses, with most cases reported in the thoracic region in the pleura. It is often considered a borderline or low-grade malignant soft tissue tumour. Complete surgical resection is currently the treatment of choice, though intracranial and orbital extension of these lesions must be carefully evaluated and navigated to ensure a safe outcome. CASE REPORT: A 36 years-old lady presented with a long one-year history of left-sided nasal obstruction with facial pain, headaches and mild visual disturbances. She had been treated for sinusitis for a prolonged period. Clinically, there was a left nasal mass obliterating the ostiomeatal complexes and the roof of the nasal cavity. MRI showed heterogeneously enhancing mass occupying the left ethmoid sinuses extending laterally eroding the left lamina papyracea to the orbit, medially towards the right nasal cavity eroding the nasal septum, and superiorly to extend intracranially. After inconclusive biopsies were performed, the mass was excised with a combined endoscopic and open lateral rhinotomy approach with left medial maxillectomy and reconstruction of the skull base defect. The tumour was eventually reported as a solitary fibrous tumour. CONCLUSIONS: Solitary fibrous tumour is a rare differential of tumours in the sino-nasal region, diagnosed via histopathology. Although generally slow-growing, these lesions may extend the adjacent structures namely the orbit and skull base. Definitive treatment via surgical resection may be performed safely after careful radiological assessment and multidisciplinary consideration.
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spelling pubmed-93929962022-08-26 A Rare Occurrence of an Extensive Sino-Nasal Solitary Fibrous Tumour Cheah, Pei Fen Ali, Azman Shanmuganathan, Jothi Iran J Otorhinolaryngol Case Report INTRODUCTION: Solitary fibrous tumours are uncommon in head and neck region, especially in the nasal cavities and paranasal sinuses, with most cases reported in the thoracic region in the pleura. It is often considered a borderline or low-grade malignant soft tissue tumour. Complete surgical resection is currently the treatment of choice, though intracranial and orbital extension of these lesions must be carefully evaluated and navigated to ensure a safe outcome. CASE REPORT: A 36 years-old lady presented with a long one-year history of left-sided nasal obstruction with facial pain, headaches and mild visual disturbances. She had been treated for sinusitis for a prolonged period. Clinically, there was a left nasal mass obliterating the ostiomeatal complexes and the roof of the nasal cavity. MRI showed heterogeneously enhancing mass occupying the left ethmoid sinuses extending laterally eroding the left lamina papyracea to the orbit, medially towards the right nasal cavity eroding the nasal septum, and superiorly to extend intracranially. After inconclusive biopsies were performed, the mass was excised with a combined endoscopic and open lateral rhinotomy approach with left medial maxillectomy and reconstruction of the skull base defect. The tumour was eventually reported as a solitary fibrous tumour. CONCLUSIONS: Solitary fibrous tumour is a rare differential of tumours in the sino-nasal region, diagnosed via histopathology. Although generally slow-growing, these lesions may extend the adjacent structures namely the orbit and skull base. Definitive treatment via surgical resection may be performed safely after careful radiological assessment and multidisciplinary consideration. Mashhad University of Medical Sciences 2022-07 /pmc/articles/PMC9392996/ /pubmed/36035651 http://dx.doi.org/10.22038/IJORL.2022.58819.3032 Text en https://creativecommons.org/licenses/by/3.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/ (https://creativecommons.org/licenses/by/3.0/) ) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Cheah, Pei Fen
Ali, Azman
Shanmuganathan, Jothi
A Rare Occurrence of an Extensive Sino-Nasal Solitary Fibrous Tumour
title A Rare Occurrence of an Extensive Sino-Nasal Solitary Fibrous Tumour
title_full A Rare Occurrence of an Extensive Sino-Nasal Solitary Fibrous Tumour
title_fullStr A Rare Occurrence of an Extensive Sino-Nasal Solitary Fibrous Tumour
title_full_unstemmed A Rare Occurrence of an Extensive Sino-Nasal Solitary Fibrous Tumour
title_short A Rare Occurrence of an Extensive Sino-Nasal Solitary Fibrous Tumour
title_sort rare occurrence of an extensive sino-nasal solitary fibrous tumour
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392996/
https://www.ncbi.nlm.nih.gov/pubmed/36035651
http://dx.doi.org/10.22038/IJORL.2022.58819.3032
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