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Giant Cell Tumor of the Carotid Body: A Rare Tumor with Malignant Potential
INTRODUCTION: Carotid body tumors (CBTs) are certainly unusual. They are vascular lesions originating from paraganglionic cells, located at the common carotid artery (CCA) bifurcation. They represent less than 0.5% of head and neck tumors, approximately 1-3 cases per million. Malignant CBTs are extr...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mashhad University of Medical Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392999/ https://www.ncbi.nlm.nih.gov/pubmed/36035645 http://dx.doi.org/10.22038/IJORL.2022.58598.3027 |
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author | Bruballa, Rocio Boccalatte, Luis Jaen, Ana Figari, Marcelo Larranaga, Juan Jose |
author_facet | Bruballa, Rocio Boccalatte, Luis Jaen, Ana Figari, Marcelo Larranaga, Juan Jose |
author_sort | Bruballa, Rocio |
collection | PubMed |
description | INTRODUCTION: Carotid body tumors (CBTs) are certainly unusual. They are vascular lesions originating from paraganglionic cells, located at the common carotid artery (CCA) bifurcation. They represent less than 0.5% of head and neck tumors, approximately 1-3 cases per million. Malignant CBTs are extremely rare; in the literature, published rates on average are < 10%. The diagnostic criteria for malignancy should be based on the finding of distant metastasis. Due to its unpredictable nature and its malignant potential, diagnosis before metastasis and complete surgical resection are the keys to a favorable prognosis. CASE REPORT: Given little experience in CBTs, its biology and treatment remain uncertain. We present the case of a 48-years-old patient, with a mass on the left side of the neck that was found to be a vast CBT with suspicious histopathology. Its size, rare location, pathologic findings, and management strategy applied for its treatment, illustrate an unusual case that highlights the importance of its publication. CONCLUSIONS: CBT is rare, but subject to cure lesion if resected without metastatic or residual disease. This is why surgery should be performed whenever possible and why it is so necessary to study this pathology thoroughly and to take it into account in the differential diagnosis. |
format | Online Article Text |
id | pubmed-9392999 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Mashhad University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-93929992022-08-26 Giant Cell Tumor of the Carotid Body: A Rare Tumor with Malignant Potential Bruballa, Rocio Boccalatte, Luis Jaen, Ana Figari, Marcelo Larranaga, Juan Jose Iran J Otorhinolaryngol Case Report INTRODUCTION: Carotid body tumors (CBTs) are certainly unusual. They are vascular lesions originating from paraganglionic cells, located at the common carotid artery (CCA) bifurcation. They represent less than 0.5% of head and neck tumors, approximately 1-3 cases per million. Malignant CBTs are extremely rare; in the literature, published rates on average are < 10%. The diagnostic criteria for malignancy should be based on the finding of distant metastasis. Due to its unpredictable nature and its malignant potential, diagnosis before metastasis and complete surgical resection are the keys to a favorable prognosis. CASE REPORT: Given little experience in CBTs, its biology and treatment remain uncertain. We present the case of a 48-years-old patient, with a mass on the left side of the neck that was found to be a vast CBT with suspicious histopathology. Its size, rare location, pathologic findings, and management strategy applied for its treatment, illustrate an unusual case that highlights the importance of its publication. CONCLUSIONS: CBT is rare, but subject to cure lesion if resected without metastatic or residual disease. This is why surgery should be performed whenever possible and why it is so necessary to study this pathology thoroughly and to take it into account in the differential diagnosis. Mashhad University of Medical Sciences 2022-07 /pmc/articles/PMC9392999/ /pubmed/36035645 http://dx.doi.org/10.22038/IJORL.2022.58598.3027 Text en https://creativecommons.org/licenses/by/3.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/ (https://creativecommons.org/licenses/by/3.0/) ) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Bruballa, Rocio Boccalatte, Luis Jaen, Ana Figari, Marcelo Larranaga, Juan Jose Giant Cell Tumor of the Carotid Body: A Rare Tumor with Malignant Potential |
title | Giant Cell Tumor of the Carotid Body: A Rare Tumor with Malignant Potential |
title_full | Giant Cell Tumor of the Carotid Body: A Rare Tumor with Malignant Potential |
title_fullStr | Giant Cell Tumor of the Carotid Body: A Rare Tumor with Malignant Potential |
title_full_unstemmed | Giant Cell Tumor of the Carotid Body: A Rare Tumor with Malignant Potential |
title_short | Giant Cell Tumor of the Carotid Body: A Rare Tumor with Malignant Potential |
title_sort | giant cell tumor of the carotid body: a rare tumor with malignant potential |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392999/ https://www.ncbi.nlm.nih.gov/pubmed/36035645 http://dx.doi.org/10.22038/IJORL.2022.58598.3027 |
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