Cargando…

Generation of two heterozygous MYBPC3 mutation-carrying human iPSC lines, SCVIi001-A and SCVIi002-A, for modeling hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is an inherited heart disease that can cause sudden cardiac death and heart failure. HCM often arises from mutations in sarcomeric genes, among which the MYBPC3 is the most frequently mutated. Here we generated two human induced pluripotent stem cell (iPSC) lines fr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Lichao, Shenoy, Sushma P., Jahng, James W.S., Liu, Yu, Knowles, Joshua W., Zhuge, Yan, Wu, Joseph C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9393020/ https://www.ncbi.nlm.nih.gov/pubmed/33743363 http://dx.doi.org/10.1016/j.scr.2021.102279

Ejemplares similares

Generation of three induced pluripotent stem cell lines, SCVIi003-A, SCVIi004-A, SCVIi005-A, from patients with ARVD/C caused by heterozygous mutations in the PKP2 gene
por: Jahng, James W.S., et al.
Publicado: (2021)

Generation of two iPSC lines from hypertrophic cardiomyopathy patients carrying MYBPC3 and PRKAG2 variants
por: Manhas, Amit, et al.
Publicado: (2022)

Heterozygous LMNA mutation-carrying iPSC lines from three cardiac laminopathy patients
por: Cho, Sangkyun, et al.
Publicado: (2022)

Fatal neonatal hypertrophic cardiomyopathy caused by compound heterozygous truncating MYBPC3 mutation
por: Alsters, S., et al.
Publicado: (2019)

Generation of three iPSC lines from dilated cardiomyopathy patients carrying a pathogenic LMNA variant
por: Lee, Chelsea, et al.
Publicado: (2022)

Evaluation of MYBPC3 trans-Splicing and Gene Replacement as Therapeutic Options in Human iPSC-Derived Cardiomyocytes
por: Prondzynski, Maksymilian, et al.
Publicado: (2017)

An Update on MYBPC3 Gene Mutation in Hypertrophic Cardiomyopathy
por: Tudurachi, Bogdan-Sorin, et al.
Publicado: (2023)

An interesting Mybpc3 heterozygous mutation associated with bicuspid aortic valve
por: Zhao, Xiaopei, et al.
Publicado: (2020)

Adverse events in families with hypertrophic or dilated cardiomyopathy and mutations in the MYBPC3 gene
por: Ehlermann, Philipp, et al.
Publicado: (2008)

Familial hypertrophic cardiomyopathy associated with a new mutation in gene MYBPC3
por: Aurensanz Clemente, Esther, et al.
Publicado: (2017)

Protein haploinsufficiency drivers identify MYBPC3 variants that cause hypertrophic cardiomyopathy
por: Suay-Corredera, Carmen, et al.
Publicado: (2021)

Establishment of NCHi009-A, an iPSC line from a patient with hypoplastic left heart syndrome (HLHS) carrying a heterozygous NOTCH1 mutation
por: Adhicary, Subhodip, et al.
Publicado: (2023)

Transcriptome Analysis of Cardiac Hypertrophic Growth in MYBPC3-Null Mice Suggests Early Responders in Hypertrophic Remodeling
por: Farrell, Emily, et al.
Publicado: (2018)

Collagen X Is Dispensable for Hypertrophic Differentiation and Endochondral Ossification of Human iPSC‐Derived Chondrocytes
por: Kamakura, Takeshi, et al.
Publicado: (2023)

Generation of three induced pluripotent stem cell lines from hypertrophic cardiomyopathy patients carrying MYH7 mutations
por: Cao, Xu, et al.
Publicado: (2021)

Modeling of dilated cardiomyopathy by establishment of isogenic human iPSC lines carrying phospholamban C25T (R9C) mutation (UPITTi002-A-1) using CRISPR/Cas9 editing
por: Barndt, Robert J., et al.
Publicado: (2021)

Generation of a gene-corrected human isogenic iPSC line from an Alzheimer’s disease iPSC line carrying the London mutation in APP (V717I)
por: Hernández, Damián, et al.
Publicado: (2021)

Phenotypic Variability in iPSC-Induced Cardiomyocytes and Cardiac Fibroblasts Carrying Diverse LMNA Mutations
por: Yang, Jiajia, et al.
Publicado: (2021)

Autosomal Recessive Transmission of MYBPC3 Mutation Results in Malignant Phenotype of Hypertrophic Cardiomyopathy
por: Wang, Yilu, et al.
Publicado: (2013)

The Metabolome in Finnish Carriers of the MYBPC3-Q1061X Mutation for Hypertrophic Cardiomyopathy
por: Jørgenrud, Benedicte, et al.
Publicado: (2015)

Myocardial Deformation Analysis in MYBPC3 and MYH7 Related Sarcomeric Hypertrophic Cardiomyopathy—The Graz Hypertrophic Cardiomyopathy Registry
por: Höller, Viktoria, et al.
Publicado: (2021)

Generation of a human Juvenile myelomonocytic leukemia iPSC line, CHOPi001-A, with a mutation in CBL
por: Gagne, Alyssa L., et al.
Publicado: (2018)

Corrigendum: Phenotypic variability in iPSC-induced cardiomyocytes and cardiac fibroblasts carrying diverse LMNA mutations
por: Yang, Jiajia, et al.
Publicado: (2022)

MYBPC3 mutations are associated with a reduced super-relaxed state in patients with hypertrophic cardiomyopathy
por: McNamara, James W., et al.
Publicado: (2017)

Reevaluation of the South Asian MYBPC3(Δ25bp) Intronic Deletion in Hypertrophic Cardiomyopathy
por: Harper, Andrew R., et al.
Publicado: (2020)

Hypertrophic cardiomyopathy in myosin-binding protein C (MYBPC3) Icelandic founder mutation carriers
por: Adalsteinsdottir, Berglind, et al.
Publicado: (2020)

Spatial and Functional Distribution of MYBPC3 Pathogenic Variants and Clinical Outcomes in Patients With Hypertrophic Cardiomyopathy
por: Helms, Adam S., et al.
Publicado: (2020)

Identification of an elusive spliceogenic MYBPC3 variant in an otherwise genotype-negative hypertrophic cardiomyopathy pedigree
por: Torrado, Mario, et al.
Publicado: (2022)

Untargeted Metabolomics Identifies Potential Hypertrophic Cardiomyopathy Biomarkers in Carriers of MYBPC3 Founder Variants
por: Jansen, Mark, et al.
Publicado: (2023)

Generation and Characterization of Novel iPSC Lines from a Portuguese Family Bearing Heterozygous and Homozygous GRN Mutations
por: Oliveira, Ana Rafaela, et al.
Publicado: (2022)

Mitochondrial Dysfunctions Contribute to Hypertrophic Cardiomyopathy in Patient iPSC-Derived Cardiomyocytes with MT-RNR2 Mutation
por: Li, Shishi, et al.
Publicado: (2018)

Skeletal dysplasia-causing TRPV4 mutations suppress the hypertrophic differentiation of human iPSC-derived chondrocytes
por: Dicks, Amanda R, et al.
Publicado: (2023)

Contractile Defect Caused by Mutation in MYBPC3 Revealed under Conditions Optimized for Human PSC-Cardiomyocyte Function
por: Birket, Matthew J., et al.
Publicado: (2015)

Increased nicotine response in iPSC-derived human neurons carrying the CHRNA5 N398 allele
por: Oni, Eileen N., et al.
Publicado: (2016)

Generation of two iPSC lines from long QT syndrome patients carrying SNTA1 variants
por: Jimenez-Tellez, Nerea, et al.
Publicado: (2023)

Banking on iPSC- Is it Doable and is it Worthwhile
por: Solomon, Susan, et al.
Publicado: (2014)

Roadblocks in the Path of iPSC to the Clinic
por: Garreta, Elena, et al.
Publicado: (2018)

iPSC Bioprinting: Where are We at?
por: Romanazzo, Sara, et al.
Publicado: (2019)

Maturing iPSC-Derived Cardiomyocytes
por: Tang, Bor Luen
Publicado: (2020)

iPSC for modeling neurodegenerative disorders
por: Valadez-Barba, Valeria, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_pa7sb0i55tovqav0v2965vso7p