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Multi-omics analysis reveals RNA splicing alterations and their biological and clinical implications in lung adenocarcinoma

Alternative RNA splicing is one of the most important mechanisms of posttranscriptional gene regulation, which contributes to protein diversity in eukaryotes. It is well known that RNA splicing dysregulation is a critical mechanism in tumor pathogenesis and the rationale for the promising splice-swi...

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Detalles Bibliográficos
Autores principales: Wu, Quanyou, Feng, Lin, Wang, Yaru, Mao, Yousheng, Di, Xuebing, Zhang, Kaitai, Cheng, Shujun, Xiao, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9393167/
https://www.ncbi.nlm.nih.gov/pubmed/35989380
http://dx.doi.org/10.1038/s41392-022-01098-5