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The Pioneer Transcription Factor Foxa2 Modulates T Helper Differentiation to Reduce Mouse Allergic Airway Disease
Foxa2, a member of the Forkhead box (Fox) family of transcription factors, plays an important role in the regulation of lung function and lung tissue homeostasis. FOXA2 expression is reduced in the lung and airways epithelium of asthmatic patients and in mice absence of Foxa2 from the lung epitheliu...
Autores principales: | Yánez, Diana C., Lau, Ching-In, Papaioannou, Eleftheria, Chawda, Mira M., Rowell, Jasmine, Ross, Susan, Furmanski, Anna, Crompton, Tessa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9393229/ https://www.ncbi.nlm.nih.gov/pubmed/36003391 http://dx.doi.org/10.3389/fimmu.2022.890781 |
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