Liposomes as Multifunctional Nano-Carriers for Medicinal Natural Products

Although medicinal natural products and their derivatives have shown promising effects in disease therapies, they usually suffer the drawbacks in low solubility and stability in the physiological environment, low delivery efficiency, side effects due to multi-targeting, and low site-specific distrib...

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Detalles Bibliográficos
Autores principales: Cheng, Xiamin, Yan, Hui, Pang, Songhao, Ya, Mingjun, Qiu, Feng, Qin, Pinzhu, Zeng, Chao, Lu, Yongna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9393238/
https://www.ncbi.nlm.nih.gov/pubmed/36003616
http://dx.doi.org/10.3389/fchem.2022.963004
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author Cheng, Xiamin
Yan, Hui
Pang, Songhao
Ya, Mingjun
Qiu, Feng
Qin, Pinzhu
Zeng, Chao
Lu, Yongna
author_facet Cheng, Xiamin
Yan, Hui
Pang, Songhao
Ya, Mingjun
Qiu, Feng
Qin, Pinzhu
Zeng, Chao
Lu, Yongna
author_sort Cheng, Xiamin
collection PubMed
description Although medicinal natural products and their derivatives have shown promising effects in disease therapies, they usually suffer the drawbacks in low solubility and stability in the physiological environment, low delivery efficiency, side effects due to multi-targeting, and low site-specific distribution in the lesion. In this review, targeted delivery was well-guided by liposomal formulation in the aspects of preparation of functional liposomes, liposomal medicinal natural products, combined therapies, and image-guided therapy. This review is believed to provide useful guidance to enhance the targeted therapy of medicinal natural products and their derivatives.
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spelling pubmed-93932382022-08-23 Liposomes as Multifunctional Nano-Carriers for Medicinal Natural Products Cheng, Xiamin Yan, Hui Pang, Songhao Ya, Mingjun Qiu, Feng Qin, Pinzhu Zeng, Chao Lu, Yongna Front Chem Chemistry Although medicinal natural products and their derivatives have shown promising effects in disease therapies, they usually suffer the drawbacks in low solubility and stability in the physiological environment, low delivery efficiency, side effects due to multi-targeting, and low site-specific distribution in the lesion. In this review, targeted delivery was well-guided by liposomal formulation in the aspects of preparation of functional liposomes, liposomal medicinal natural products, combined therapies, and image-guided therapy. This review is believed to provide useful guidance to enhance the targeted therapy of medicinal natural products and their derivatives. Frontiers Media S.A. 2022-08-08 /pmc/articles/PMC9393238/ /pubmed/36003616 http://dx.doi.org/10.3389/fchem.2022.963004 Text en Copyright © 2022 Cheng, Yan, Pang, Ya, Qiu, Qin, Zeng and Lu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Chemistry
Cheng, Xiamin
Yan, Hui
Pang, Songhao
Ya, Mingjun
Qiu, Feng
Qin, Pinzhu
Zeng, Chao
Lu, Yongna
Liposomes as Multifunctional Nano-Carriers for Medicinal Natural Products
title Liposomes as Multifunctional Nano-Carriers for Medicinal Natural Products
title_full Liposomes as Multifunctional Nano-Carriers for Medicinal Natural Products
title_fullStr Liposomes as Multifunctional Nano-Carriers for Medicinal Natural Products
title_full_unstemmed Liposomes as Multifunctional Nano-Carriers for Medicinal Natural Products
title_short Liposomes as Multifunctional Nano-Carriers for Medicinal Natural Products
title_sort liposomes as multifunctional nano-carriers for medicinal natural products
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9393238/
https://www.ncbi.nlm.nih.gov/pubmed/36003616
http://dx.doi.org/10.3389/fchem.2022.963004
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