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Distribution of HLA-B Alleles and Haplotypes in Qatari: Recommendation for Establishing Pharmacogenomic Markers Screening for Drug Hypersensitivity

Human leukocyte antigen (HLA) proteins are present at the cellular surface of antigen-presenting cells and play a crucial role in the adaptive immune response. Class I genes, specifically certain HLA-B alleles, are associated with adverse drug reactions (ADRs) and are used as pharmacogenetic markers...

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Detalles Bibliográficos
Autores principales:	Dashti, Mohammed, Al-Matrouk, Abdullah, Channanath, Arshad, Hebbar, Prashantha, Al-Mulla, Fahd, Thanaraj, Thangavel Alphonse
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9393242/ https://www.ncbi.nlm.nih.gov/pubmed/36003520 http://dx.doi.org/10.3389/fphar.2022.891838

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