Seed-induced Aβ deposits in the corpus callosum disrupt white matter integrity in a mouse model of Alzheimer’s disease

Neuropathologically, Alzheimer’s disease (AD) is characterized by the accumulation of amyloid-beta peptide (Aβ) and subsequent formation of the so-called Aβ plaques. Along with neuronal loss, previous studies report white matter anomalies and corpus callosum (CC) atrophy in AD patients. Notably, per...

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Detalles Bibliográficos
Autores principales: Aires, Vanessa, Ziegler-Waldkirch, Stephanie, Friesen, Marina, Reichardt, Wilfried, Erny, Daniel, Loreth, Desiree, Harborne, Andrew, Kretz, Oliver, von Elverfeldt, Dominik, Meyer-Luehmann, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9393256/
https://www.ncbi.nlm.nih.gov/pubmed/36003141
http://dx.doi.org/10.3389/fncel.2022.862918

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