Cargando…
TGF-β regulates the stem-like state of PD-1(+) TCF-1(+) virus-specific CD8 T cells during chronic infection
Recent studies have defined a novel population of PD-1(+) TCF-1(+) stem-like CD8 T cells in chronic infections and cancer. These quiescent cells reside in lymphoid tissues, are critical for maintaining the CD8 T cell response under conditions of persistent antigen, and provide the proliferative burs...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9393409/ https://www.ncbi.nlm.nih.gov/pubmed/35980386 http://dx.doi.org/10.1084/jem.20211574 |