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TGF-β regulates the stem-like state of PD-1(+) TCF-1(+) virus-specific CD8 T cells during chronic infection

Recent studies have defined a novel population of PD-1(+) TCF-1(+) stem-like CD8 T cells in chronic infections and cancer. These quiescent cells reside in lymphoid tissues, are critical for maintaining the CD8 T cell response under conditions of persistent antigen, and provide the proliferative burs...

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Detalles Bibliográficos
Autores principales: Hu, Yinghong, Hudson, William H., Kissick, Haydn T., Medina, Christopher B., Baptista, Antonio P., Ma, Chaoyu, Liao, Wei, Germain, Ronald N., Turley, Shannon J., Zhang, Nu, Ahmed, Rafi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9393409/
https://www.ncbi.nlm.nih.gov/pubmed/35980386
http://dx.doi.org/10.1084/jem.20211574

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