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Upregulated integrin α11 in the stroma of cutaneous squamous cell carcinoma promotes skin carcinogenesis

Integrin α11β1 is a collagen-binding integrin that is needed to induce and maintain the myofibroblast phenotype in fibrotic tissues and during wound healing. The expression of the α11 is upregulated in cancer-associated fibroblasts (CAFs) in various human neoplasms. We investigated α11 expression in...

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Detalles Bibliográficos
Autores principales: Martínez-Nieto, Guillermo A., Teppo, Hanna-Riikka, Petrelius, Noora, Izzi, Valerio, Devarajan, Raman, Petäistö, Tiina, Liu, Hengshuo, Kim, Kris S., Karppinen, Sanna-Maria, Ruotsalainen, Heli, Koivunen, Jarkko, Mäki, Joni M., Walker, Gilbert C., Pihlajaniemi, Taina, Gullberg, Donald, Heljasvaara, Ritva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9393502/
https://www.ncbi.nlm.nih.gov/pubmed/36003785
http://dx.doi.org/10.3389/fonc.2022.981009