Cargando…
EST12 regulates Myc expression and enhances anti-mycobacterial inflammatory response via RACK1-JNK-AP1-Myc immune pathway
c-Myc (Myc) is a well-known transcription factor that regulates many essential cellular processes. Myc has been implicated in regulating anti-mycobacterial responses. However, its precise mechanism in modulating mycobacterial immunity remains elusive. Here, we found that a secreted Rv1579c (early se...
Autores principales: | Wu, Jian, Luo, Feng-Ling, Xie, Yan, Xiong, Huan, Gao, Yadong, Liu, Guanghui, Zhang, Xiao-Lian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9393728/ https://www.ncbi.nlm.nih.gov/pubmed/36003390 http://dx.doi.org/10.3389/fimmu.2022.943174 |
Ejemplares similares
-
Mycobacterial EST12 activates a RACK1–NLRP3–gasdermin D pyroptosis–IL-1β immune pathway
por: Qu, Zilu, et al.
Publicado: (2020) -
JNK/AP1 Pathway Regulates MYC Expression and BCR Signaling through Ig Enhancers in Burkitt Lymphoma Cells
por: Ding, Xiaoling, et al.
Publicado: (2020) -
Lnc-EST12, which is negatively regulated by mycobacterial EST12, suppresses antimycobacterial innate immunity through its interaction with FUBP3
por: Yao, Qili, et al.
Publicado: (2022) -
Radiotherapy-Associated Long-term Modification of Expression of the Inflammatory Biomarker Genes ARG1, BCL2L1, and MYC
por: Manning, Grainne, et al.
Publicado: (2017) -
TOP1 inhibition induces bifurcated JNK/MYC signaling that dictates cancer cell sensitivity
por: Liu, Qizhi, et al.
Publicado: (2022)