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Ruxolitinib Re-Treatment in Patients with Myelofibrosis: Real-World Evidence on Patient Characteristics and Outcomes
Ruxolitinib is an FDA-approved treatment of intermediate- and high-risk myelofibrosis. In the phase 3 COMFORT studies, ruxolitinib reduced spleen volume in patients with myelofibrosis, with a median time to response of 3 months. However, nearly 20% of patients discontinued by month 4 with few treatm...
Autores principales: | Gerds, Aaron T., Yu, Jingbo, Scherber, Robyn M., Paranagama, Dilan, Kish, Jonathan K., Visaria, Jay, Singhal, Mukul, Verstovsek, Srdan, Pemmaraju, Naveen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9393808/ https://www.ncbi.nlm.nih.gov/pubmed/35008087 http://dx.doi.org/10.1159/000520440 |
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