Cargando…

Trophoblast Cell Surface Antigen 2 Expression in Human Tumors: A Tissue Microarray Study on 18,563 Tumors

INTRODUCTION: Trophoblast cell surface antigen 2 (TROP2) is the target of sacituzumab govitecan, an antibody-drug conjugate approved for treatment of triple negative breast cancer and urothelial carcinoma. METHODS: A tissue microarray containing 18,563 samples from 150 different tumor types and subt...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dum, David, Taherpour, Noushin, Menz, Anne, Höflmayer, Doris, Völkel, Cosima, Hinsch, Andrea, Gorbokon, Natalia, Lennartz, Maximilian, Hube-Magg, Claudia, Fraune, Christoph, Bernreuther, Christian, Lebok, Patrick, Clauditz, Till S., Jacobsen, Frank, Sauter, Guido, Uhlig, Ria, Wilczak, Waldemar, Steurer, Stefan, Minner, Sarah, Marx, Andreas H., Simon, Ronald, Burandt, Eike, Krech, Till, Luebke, Andreas M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	S. Karger AG 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9393818/ https://www.ncbi.nlm.nih.gov/pubmed/35477165 http://dx.doi.org/10.1159/000522206

Ejemplares similares

Mammaglobin-A Expression Is Highly Specific for Tumors Derived from the Breast, the Female Genital Tract, and the Salivary Gland
por: Gorbokon, Natalia, et al.
Publicado: (2023)

Pan-keratin Immunostaining in Human Tumors: A Tissue Microarray Study of 15,940 Tumors
por: Menz, Anne, et al.
Publicado: (2022)

Diagnostic and prognostic impact of cytokeratin 18 expression in human tumors: a tissue microarray study on 11,952 tumors
por: Menz, Anne, et al.
Publicado: (2021)

Large-Scale Tissue Microarray Evaluation Corroborates High Specificity of High-Level Arginase-1 Immunostaining for Hepatocellular Carcinoma
por: Lennartz, Maximilian, et al.
Publicado: (2021)

E-Cadherin expression in human tumors: a tissue microarray study on 10,851 tumors
por: Burandt, Eike, et al.
Publicado: (2021)

Diagnostic and Prognostic Impact of Progesterone Receptor Immunohistochemistry: A Study Evaluating More Than 16,000 Tumors
por: Viehweger, Florian, et al.
Publicado: (2022)

Cytokeratin 5 and cytokeratin 6 expressions are unconnected in normal and cancerous tissues and have separate diagnostic implications
por: Völkel, Cosima, et al.
Publicado: (2021)

Carboxypeptidase A1 (CPA1) Immunohistochemistry Is Highly Sensitive and Specific for Acinar Cell Carcinoma (ACC) of the Pancreas
por: Uhlig, Ria, et al.
Publicado: (2022)

CELA3B immunostaining is a highly specific marker for acinar cell carcinoma of the pancreas
por: Uhlig, Ria, et al.
Publicado: (2023)

FABP1 expression in human tumors: a tissue microarray study on 17,071 tumors
por: Dum, David, et al.
Publicado: (2022)

Napsin A Expression in Human Tumors and Normal Tissues
por: Weidemann, Sören, et al.
Publicado: (2021)

p63 expression in human tumors and normal tissues: a tissue microarray study on 10,200 tumors
por: Steurer, Stefan, et al.
Publicado: (2021)

High prevalence of p16 staining in malignant tumors
por: De Wispelaere, Noémi, et al.
Publicado: (2022)

Cadherin-16 (CDH16) immunohistochemistry: a useful diagnostic tool for renal cell carcinoma and papillary carcinomas of the thyroid
por: Lennartz, Maximilian, et al.
Publicado: (2023)

MUC5AC Expression in Various Tumor Types and Nonneoplastic Tissue: A Tissue Microarray Study on 10 399 Tissue Samples
por: Rico, Sebastian Dwertmann, et al.
Publicado: (2021)

Mesothelin Expression in Human Tumors: A Tissue Microarray Study on 12,679 Tumors
por: Weidemann, Sören, et al.
Publicado: (2021)

Pattern of placental alkaline phosphatase (PLAP) expression in human tumors: a tissue microarray study on 12,381 tumors
por: Reiswich, Viktor, et al.
Publicado: (2021)

Analysis of More than 16,000 Human Tumor and Normal Tissues Identifies Uroplakin 3B as a Useful Diagnostic Marker for Mesothelioma and Normal Mesothelial Cells
por: Lennartz, Maximilian, et al.
Publicado: (2022)

Inhibin Alpha Expression in Human Tumors: A Tissue Microarray Study on 12,212 Tumors
por: Weidemann, Sören, et al.
Publicado: (2022)

Angiotensin-Converting Enzyme 2 Protein Is Overexpressed in a Wide Range of Human Tumour Types: A Systematic Tissue Microarray Study on >15,000 Tumours
por: Meiners, Jan, et al.
Publicado: (2021)

High Homogeneity of Mesothelin Expression in Primary and Metastatic Ovarian Cancer
por: Weidemann, Sören, et al.
Publicado: (2023)

Mucin 5AC expression is common but unrelated to tumor progression in pancreatic adenocarcinoma
por: Dwertmann Rico, Sebastian, et al.
Publicado: (2022)

Prognostic role of proliferating CD8(+) cytotoxic Tcells in human cancers
por: Blessin, Niclas C., et al.
Publicado: (2021)

Diagnostic Role and Prognostic Impact of PSAP Immunohistochemistry: A Tissue Microarray Study on 31,358 Cancer Tissues
por: Tribian, Laura Sophie, et al.
Publicado: (2023)

PD-L1 expression and CD8 positive lymphocytes in human neoplasms: A tissue microarray study on 11,838 tumor samples
por: Möller, Katharina, et al.
Publicado: (2023)

Prevalence of CD8(+) cytotoxic lymphocytes in human neoplasms
por: Blessin, Niclas C., et al.
Publicado: (2020)

Semi-automated validation and quantification of CTLA-4 in 90 different tumor entities using multiple antibodies and artificial intelligence
por: Dum, David, et al.
Publicado: (2022)

A nuclear shift of GSK3β protein is an independent prognostic factor in prostate cancer
por: Eichenauer, Till, et al.
Publicado: (2019)

Patterns of TIGIT Expression in Lymphatic Tissue, Inflammation, and Cancer
por: Blessin, Niclas C., et al.
Publicado: (2019)

Expression of the immune checkpoint receptor TIGIT in seminoma
por: Hinsch, Andrea, et al.
Publicado: (2019)

Elevated MUC5AC expression is associated with mismatch repair deficiency and proximal tumor location but not with cancer progression in colon cancer
por: Rico, Sebastian Dwertmann, et al.
Publicado: (2020)

SNW1 is a prognostic biomarker in prostate cancer
por: Höflmayer, Doris, et al.
Publicado: (2019)

Expression of the immune checkpoint receptor TIGIT in Hodgkin’s lymphoma
por: Li, Wenchao, et al.
Publicado: (2018)

Upregulation of the heterogeneous nuclear ribonucleoprotein hnRNPA1 is an independent predictor of early biochemical recurrence in TMPRSS2:ERG fusion-negative prostate cancers
por: Möller, Katharina, et al.
Publicado: (2020)

Secreted Frizzled-Related Protein 4 (SFRP4) Is an Independent Prognostic Marker in Prostate Cancers Lacking TMPRSS2: ERG Fusions
por: Bernreuther, Christian, et al.
Publicado: (2020)

Prevalence of proliferating CD8(+) cells in normal lymphatic tissues, inflammation and cancer
por: Blessin, Niclas C., et al.
Publicado: (2021)

Down-Regulation of S100A8 is an Independent Predictor of PSA Recurrence in Prostate Cancer Treated by Radical Prostatectomy()
por: Minner, Sarah, et al.
Publicado: (2019)

Upregulation of Phosphatase 1 Nuclear-Targeting Subunit (PNUTS) Is an Independent Predictor of Poor Prognosis in Prostate Cancer
por: Marx, Andreas, et al.
Publicado: (2020)

Homogeneous MMR Deficiency Throughout the Entire Tumor Mass Occurs in a Subset of Colorectal Neuroendocrine Carcinomas
por: Fraune, Christoph, et al.
Publicado: (2020)

BLEACH&STAIN 15-marker Multiplexed Imaging in 3,098 Human Carcinomas Reveals Six Major PD-L1–driven Immune Phenotypes with Distinct Spatial Orchestration
por: Bady, Elena, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_bqub41oi84a48u8hkifvotoga1