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Chromosome instability and aneuploidy as context-dependent activators or inhibitors of antitumor immunity
Chromosome instability (CIN) and its major consequence, aneuploidy, are hallmarks of human cancers. In addition to imposing fitness costs on tumor cells through several cell-intrinsic mechanisms, CIN/aneuploidy also provokes an antitumor immune response. However, as the major contributor to genomic...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9393846/ https://www.ncbi.nlm.nih.gov/pubmed/36003402 http://dx.doi.org/10.3389/fimmu.2022.895961 |