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Evolution of intra-tumoral heterogeneity across different pathological stages in papillary thyroid carcinoma

BACKGROUND: Intra-tumor heterogeneity (ITH) results from the continuous accumulation of mutations during disease progression, thus impacting patients’ clinical outcome. How the ITH evolves across papillary thyroid carcinoma (PTC) different tumor stages is lacking. METHODS: We used the whole-exome se...

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Detalles Bibliográficos
Autores principales:	Affinito, Ornella, Orlandella, Francesca Maria, Luciano, Neila, Salvatore, Marco, Salvatore, Giuliana, Franzese, Monica
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394008/ https://www.ncbi.nlm.nih.gov/pubmed/35996174 http://dx.doi.org/10.1186/s12935-022-02680-1

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