Spinal intramedullary hemangioblastoma and schwannoma collision tumor: illustrative case

BACKGROUND: Intramedullary spinal cord tumors represent a minority of intradural tumors. Among intramedullary spinal cord tumors, hemangioblastomas are uncommon, and schwannomas are extremely rare. Collision tumors are histologically distinct tumors that are intermingled and growing together. OBSERV...

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Autores principales: Neal, Matthew T., Richards, Alexandra E., Curley, Kara L., Donev, Kliment, Lyons, Mark K., Kalani, Maziyar A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association of Neurological Surgeons 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394162/
https://www.ncbi.nlm.nih.gov/pubmed/36034507
http://dx.doi.org/10.3171/CASE2059
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author Neal, Matthew T.
Richards, Alexandra E.
Curley, Kara L.
Donev, Kliment
Lyons, Mark K.
Kalani, Maziyar A.
author_facet Neal, Matthew T.
Richards, Alexandra E.
Curley, Kara L.
Donev, Kliment
Lyons, Mark K.
Kalani, Maziyar A.
author_sort Neal, Matthew T.
collection PubMed
description BACKGROUND: Intramedullary spinal cord tumors represent a minority of intradural tumors. Among intramedullary spinal cord tumors, hemangioblastomas are uncommon, and schwannomas are extremely rare. Collision tumors are histologically distinct tumors that are intermingled and growing together. OBSERVATIONS: In this report, the authors describe a patient with a cervical intramedullary collision tumor involving a hemangioblastoma and schwannoma. To the authors’ knowledge, no prior spinal intramedullary collision tumor involving multiple neoplasms has been described. The patient’s presentation and management are described. LESSONS: Clinicians should consider the possibility of collision tumors when evaluating intramedullary spinal cord tumors, especially when patient presentation and radiographic findings are atypical. When tumors with similar radiographic characteristics form collision tumors, distinction using preoperative imaging can be extremely challenging. In addition, surgical management of intramedullary collision tumors, like that for all intramedullary spinal cord tumors, should involve meticulous perioperative care and a methodical surgical technique. Maximal safe resection will depend upon histopathological diagnosis, anatomical location of the tumor, presence of distinct dissection planes, and stability of neuromonitoring. Finally, ongoing research on the genetics of intramedullary spinal cord tumors may identify underlying genetic links for intramedullary hemangioblastomas and schwannomas.
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spelling pubmed-93941622022-08-25 Spinal intramedullary hemangioblastoma and schwannoma collision tumor: illustrative case Neal, Matthew T. Richards, Alexandra E. Curley, Kara L. Donev, Kliment Lyons, Mark K. Kalani, Maziyar A. J Neurosurg Case Lessons Case Report BACKGROUND: Intramedullary spinal cord tumors represent a minority of intradural tumors. Among intramedullary spinal cord tumors, hemangioblastomas are uncommon, and schwannomas are extremely rare. Collision tumors are histologically distinct tumors that are intermingled and growing together. OBSERVATIONS: In this report, the authors describe a patient with a cervical intramedullary collision tumor involving a hemangioblastoma and schwannoma. To the authors’ knowledge, no prior spinal intramedullary collision tumor involving multiple neoplasms has been described. The patient’s presentation and management are described. LESSONS: Clinicians should consider the possibility of collision tumors when evaluating intramedullary spinal cord tumors, especially when patient presentation and radiographic findings are atypical. When tumors with similar radiographic characteristics form collision tumors, distinction using preoperative imaging can be extremely challenging. In addition, surgical management of intramedullary collision tumors, like that for all intramedullary spinal cord tumors, should involve meticulous perioperative care and a methodical surgical technique. Maximal safe resection will depend upon histopathological diagnosis, anatomical location of the tumor, presence of distinct dissection planes, and stability of neuromonitoring. Finally, ongoing research on the genetics of intramedullary spinal cord tumors may identify underlying genetic links for intramedullary hemangioblastomas and schwannomas. American Association of Neurological Surgeons 2021-01-18 /pmc/articles/PMC9394162/ /pubmed/36034507 http://dx.doi.org/10.3171/CASE2059 Text en © 2021 The authors, https://creativecommons.org/licenses/by-nc-nd/4.0/CC BY-NC-ND 4.0 (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ).
spellingShingle Case Report
Neal, Matthew T.
Richards, Alexandra E.
Curley, Kara L.
Donev, Kliment
Lyons, Mark K.
Kalani, Maziyar A.
Spinal intramedullary hemangioblastoma and schwannoma collision tumor: illustrative case
title Spinal intramedullary hemangioblastoma and schwannoma collision tumor: illustrative case
title_full Spinal intramedullary hemangioblastoma and schwannoma collision tumor: illustrative case
title_fullStr Spinal intramedullary hemangioblastoma and schwannoma collision tumor: illustrative case
title_full_unstemmed Spinal intramedullary hemangioblastoma and schwannoma collision tumor: illustrative case
title_short Spinal intramedullary hemangioblastoma and schwannoma collision tumor: illustrative case
title_sort spinal intramedullary hemangioblastoma and schwannoma collision tumor: illustrative case
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394162/
https://www.ncbi.nlm.nih.gov/pubmed/36034507
http://dx.doi.org/10.3171/CASE2059
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