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Molecular Epidemiology of Genital Infections in Campania Region: A Retrospective Study
This study provides updated information on the prevalence and co-infections caused by genital microorganisms and pathogens: Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma parvum, Ureaplasma urealyticum, Trichomonas vaginalis, and Gardnerella vaginalis, by retrospectively analyzing a cohort of...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394247/ https://www.ncbi.nlm.nih.gov/pubmed/35892509 http://dx.doi.org/10.3390/diagnostics12081798 |
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author | Scaglione, Elena Mantova, Giuseppe Caturano, Valeria Fanasca, Luca Carraturo, Francesca Farina, Fabrizio Pagliarulo, Caterina Vitiello, Mariateresa Pagliuca, Chiara Salvatore, Paola Colicchio, Roberta |
author_facet | Scaglione, Elena Mantova, Giuseppe Caturano, Valeria Fanasca, Luca Carraturo, Francesca Farina, Fabrizio Pagliarulo, Caterina Vitiello, Mariateresa Pagliuca, Chiara Salvatore, Paola Colicchio, Roberta |
author_sort | Scaglione, Elena |
collection | PubMed |
description | This study provides updated information on the prevalence and co-infections caused by genital microorganisms and pathogens: Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma parvum, Ureaplasma urealyticum, Trichomonas vaginalis, and Gardnerella vaginalis, by retrospectively analyzing a cohort of patients living in the Naples metropolitan area, Campania region, Southern Italy. To investigate the genital infections prevalence in clinical specimens (vaginal/endocervical swabs and urines) collected from infertile asymptomatic women and men from November 2018 to December 2020, we used a multiplex real-time PCR assay. Of the 717 specimens collected, 302 (42.1%) resulted positive for at least one of the targets named above. Statistically significant differences in genital prevalence of selected microorganisms were detected in both women (62.91%) and men (37.08%). G. vaginalis and U. parvum represented the most common findings with an 80.2% and 16.9% prevalence in vaginal/endocervical swabs and first-voided urines, respectively. Prevalence of multiple infections was 18.18% and 8.19% in women and men, respectively. The most frequent association detected was the co-infection of G. vaginalis and U. parvum with 60% prevalence. Our epidemiological analysis suggests different infection patterns between genders, highlighting the need to implement a preventative screening strategy of genital infections to reduce the complications on reproductive organs. |
format | Online Article Text |
id | pubmed-9394247 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-93942472022-08-23 Molecular Epidemiology of Genital Infections in Campania Region: A Retrospective Study Scaglione, Elena Mantova, Giuseppe Caturano, Valeria Fanasca, Luca Carraturo, Francesca Farina, Fabrizio Pagliarulo, Caterina Vitiello, Mariateresa Pagliuca, Chiara Salvatore, Paola Colicchio, Roberta Diagnostics (Basel) Article This study provides updated information on the prevalence and co-infections caused by genital microorganisms and pathogens: Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma parvum, Ureaplasma urealyticum, Trichomonas vaginalis, and Gardnerella vaginalis, by retrospectively analyzing a cohort of patients living in the Naples metropolitan area, Campania region, Southern Italy. To investigate the genital infections prevalence in clinical specimens (vaginal/endocervical swabs and urines) collected from infertile asymptomatic women and men from November 2018 to December 2020, we used a multiplex real-time PCR assay. Of the 717 specimens collected, 302 (42.1%) resulted positive for at least one of the targets named above. Statistically significant differences in genital prevalence of selected microorganisms were detected in both women (62.91%) and men (37.08%). G. vaginalis and U. parvum represented the most common findings with an 80.2% and 16.9% prevalence in vaginal/endocervical swabs and first-voided urines, respectively. Prevalence of multiple infections was 18.18% and 8.19% in women and men, respectively. The most frequent association detected was the co-infection of G. vaginalis and U. parvum with 60% prevalence. Our epidemiological analysis suggests different infection patterns between genders, highlighting the need to implement a preventative screening strategy of genital infections to reduce the complications on reproductive organs. MDPI 2022-07-25 /pmc/articles/PMC9394247/ /pubmed/35892509 http://dx.doi.org/10.3390/diagnostics12081798 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Scaglione, Elena Mantova, Giuseppe Caturano, Valeria Fanasca, Luca Carraturo, Francesca Farina, Fabrizio Pagliarulo, Caterina Vitiello, Mariateresa Pagliuca, Chiara Salvatore, Paola Colicchio, Roberta Molecular Epidemiology of Genital Infections in Campania Region: A Retrospective Study |
title | Molecular Epidemiology of Genital Infections in Campania Region: A Retrospective Study |
title_full | Molecular Epidemiology of Genital Infections in Campania Region: A Retrospective Study |
title_fullStr | Molecular Epidemiology of Genital Infections in Campania Region: A Retrospective Study |
title_full_unstemmed | Molecular Epidemiology of Genital Infections in Campania Region: A Retrospective Study |
title_short | Molecular Epidemiology of Genital Infections in Campania Region: A Retrospective Study |
title_sort | molecular epidemiology of genital infections in campania region: a retrospective study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394247/ https://www.ncbi.nlm.nih.gov/pubmed/35892509 http://dx.doi.org/10.3390/diagnostics12081798 |
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