Cargando…

Thermally Drawn CNT-Based Hybrid Nanocomposite Fiber for Electrochemical Sensing

Nowadays, bioelectronic devices are evolving from rigid to flexible materials and substrates, among which thermally-drawn-fiber-based bioelectronics represent promising technologies thanks to their inherent flexibility and seamless integration of multi-functionalities. However, electrochemical sensi...

Descripción completa

Detalles Bibliográficos
Autores principales: Nishimoto, Rino, Sato, Yuichi, Wu, Jingxuan, Saizaki, Tomoki, Kubo, Mahiro, Wang, Mengyun, Abe, Hiroya, Richard, Inès, Yoshinobu, Tatsuo, Sorin, Fabien, Guo, Yuanyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394265/
https://www.ncbi.nlm.nih.gov/pubmed/35892456
http://dx.doi.org/10.3390/bios12080559
_version_ 1784771450215858176
author Nishimoto, Rino
Sato, Yuichi
Wu, Jingxuan
Saizaki, Tomoki
Kubo, Mahiro
Wang, Mengyun
Abe, Hiroya
Richard, Inès
Yoshinobu, Tatsuo
Sorin, Fabien
Guo, Yuanyuan
author_facet Nishimoto, Rino
Sato, Yuichi
Wu, Jingxuan
Saizaki, Tomoki
Kubo, Mahiro
Wang, Mengyun
Abe, Hiroya
Richard, Inès
Yoshinobu, Tatsuo
Sorin, Fabien
Guo, Yuanyuan
author_sort Nishimoto, Rino
collection PubMed
description Nowadays, bioelectronic devices are evolving from rigid to flexible materials and substrates, among which thermally-drawn-fiber-based bioelectronics represent promising technologies thanks to their inherent flexibility and seamless integration of multi-functionalities. However, electrochemical sensing within fibers remains a poorly explored area, as it imposes new demands for material properties—both the electrochemical sensitivity and the thermomechanical compatibility with the fiber drawing process. Here, we designed and fabricated microelectrode fibers made of carbon nanotube (CNT)-based hybrid nanocomposites and further evaluated their detailed electrochemical sensing performances. Carbon-black-impregnated polyethylene (CB-CPE) was chosen as the base material, into which CNT was loaded homogeneously in a concentration range of 3.8 to 10 wt%. First, electrical impedance characterization of CNT nanocomposites showed a remarkable decrease of the resistance with the increase in CNT loading ratio, suggesting that CNTs notably increased the effective electrical current pathways inside the composites. In addition, the proof-of-principle performance of fiber-based microelectrodes was characterized for the detection of ferrocenemethanol (FcMeOH) and dopamine (DA), exhibiting an ultra-high sensitivity. Additionally, we further examined the long-term stability of such composite-based electrode in exposure to the aqueous environment, mimicking the in vivo or in vitro settings. Later, we functionalized the surface of the microelectrode fiber with ion-sensitive membranes (ISM) for the selective sensing of Na [Formula: see text] ions. The miniature fiber-based electrochemical sensor developed here holds great potential for standalone point-of-care sensing applications. In the future, taking full advantage of the thermal drawing process, the electrical, optical, chemical, and electrochemical modalities can be all integrated together within a thin strand of fiber. This single fiber can be useful for fundamental multi-mechanistic studies for biological applications and the weaved fibers can be further applied for daily health monitoring as functional textiles.
format Online
Article
Text
id pubmed-9394265
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-93942652022-08-23 Thermally Drawn CNT-Based Hybrid Nanocomposite Fiber for Electrochemical Sensing Nishimoto, Rino Sato, Yuichi Wu, Jingxuan Saizaki, Tomoki Kubo, Mahiro Wang, Mengyun Abe, Hiroya Richard, Inès Yoshinobu, Tatsuo Sorin, Fabien Guo, Yuanyuan Biosensors (Basel) Article Nowadays, bioelectronic devices are evolving from rigid to flexible materials and substrates, among which thermally-drawn-fiber-based bioelectronics represent promising technologies thanks to their inherent flexibility and seamless integration of multi-functionalities. However, electrochemical sensing within fibers remains a poorly explored area, as it imposes new demands for material properties—both the electrochemical sensitivity and the thermomechanical compatibility with the fiber drawing process. Here, we designed and fabricated microelectrode fibers made of carbon nanotube (CNT)-based hybrid nanocomposites and further evaluated their detailed electrochemical sensing performances. Carbon-black-impregnated polyethylene (CB-CPE) was chosen as the base material, into which CNT was loaded homogeneously in a concentration range of 3.8 to 10 wt%. First, electrical impedance characterization of CNT nanocomposites showed a remarkable decrease of the resistance with the increase in CNT loading ratio, suggesting that CNTs notably increased the effective electrical current pathways inside the composites. In addition, the proof-of-principle performance of fiber-based microelectrodes was characterized for the detection of ferrocenemethanol (FcMeOH) and dopamine (DA), exhibiting an ultra-high sensitivity. Additionally, we further examined the long-term stability of such composite-based electrode in exposure to the aqueous environment, mimicking the in vivo or in vitro settings. Later, we functionalized the surface of the microelectrode fiber with ion-sensitive membranes (ISM) for the selective sensing of Na [Formula: see text] ions. The miniature fiber-based electrochemical sensor developed here holds great potential for standalone point-of-care sensing applications. In the future, taking full advantage of the thermal drawing process, the electrical, optical, chemical, and electrochemical modalities can be all integrated together within a thin strand of fiber. This single fiber can be useful for fundamental multi-mechanistic studies for biological applications and the weaved fibers can be further applied for daily health monitoring as functional textiles. MDPI 2022-07-24 /pmc/articles/PMC9394265/ /pubmed/35892456 http://dx.doi.org/10.3390/bios12080559 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Nishimoto, Rino
Sato, Yuichi
Wu, Jingxuan
Saizaki, Tomoki
Kubo, Mahiro
Wang, Mengyun
Abe, Hiroya
Richard, Inès
Yoshinobu, Tatsuo
Sorin, Fabien
Guo, Yuanyuan
Thermally Drawn CNT-Based Hybrid Nanocomposite Fiber for Electrochemical Sensing
title Thermally Drawn CNT-Based Hybrid Nanocomposite Fiber for Electrochemical Sensing
title_full Thermally Drawn CNT-Based Hybrid Nanocomposite Fiber for Electrochemical Sensing
title_fullStr Thermally Drawn CNT-Based Hybrid Nanocomposite Fiber for Electrochemical Sensing
title_full_unstemmed Thermally Drawn CNT-Based Hybrid Nanocomposite Fiber for Electrochemical Sensing
title_short Thermally Drawn CNT-Based Hybrid Nanocomposite Fiber for Electrochemical Sensing
title_sort thermally drawn cnt-based hybrid nanocomposite fiber for electrochemical sensing
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394265/
https://www.ncbi.nlm.nih.gov/pubmed/35892456
http://dx.doi.org/10.3390/bios12080559
work_keys_str_mv AT nishimotorino thermallydrawncntbasedhybridnanocompositefiberforelectrochemicalsensing
AT satoyuichi thermallydrawncntbasedhybridnanocompositefiberforelectrochemicalsensing
AT wujingxuan thermallydrawncntbasedhybridnanocompositefiberforelectrochemicalsensing
AT saizakitomoki thermallydrawncntbasedhybridnanocompositefiberforelectrochemicalsensing
AT kubomahiro thermallydrawncntbasedhybridnanocompositefiberforelectrochemicalsensing
AT wangmengyun thermallydrawncntbasedhybridnanocompositefiberforelectrochemicalsensing
AT abehiroya thermallydrawncntbasedhybridnanocompositefiberforelectrochemicalsensing
AT richardines thermallydrawncntbasedhybridnanocompositefiberforelectrochemicalsensing
AT yoshinobutatsuo thermallydrawncntbasedhybridnanocompositefiberforelectrochemicalsensing
AT sorinfabien thermallydrawncntbasedhybridnanocompositefiberforelectrochemicalsensing
AT guoyuanyuan thermallydrawncntbasedhybridnanocompositefiberforelectrochemicalsensing