Pharmacological Targets in Chronic Heart Failure with Reduced Ejection Fraction

Heart failure management has been repeatedly reviewed over time. This strategy has resulted in improved quality of life, especially in patients with heart failure with reduced ejection fraction (HFrEF). It is for this reason that new mechanisms involved in the development and progression of heart fa...

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Autores principales: Moloce, Maria-Angela, Costache, Irina-Iuliana, Nicolae, Ana, Onofrei Aursulesei, Viviana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394280/
https://www.ncbi.nlm.nih.gov/pubmed/35892914
http://dx.doi.org/10.3390/life12081112
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author Moloce, Maria-Angela
Costache, Irina-Iuliana
Nicolae, Ana
Onofrei Aursulesei, Viviana
author_facet Moloce, Maria-Angela
Costache, Irina-Iuliana
Nicolae, Ana
Onofrei Aursulesei, Viviana
author_sort Moloce, Maria-Angela
collection PubMed
description Heart failure management has been repeatedly reviewed over time. This strategy has resulted in improved quality of life, especially in patients with heart failure with reduced ejection fraction (HFrEF). It is for this reason that new mechanisms involved in the development and progression of heart failure, along with specific therapies, have been identified. This review focuses on the most recent guidelines of therapeutic interventions, trials that explore novel therapies, and also new molecules that could improve prognosis of different HFrEF phenotypes.
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spelling pubmed-93942802022-08-23 Pharmacological Targets in Chronic Heart Failure with Reduced Ejection Fraction Moloce, Maria-Angela Costache, Irina-Iuliana Nicolae, Ana Onofrei Aursulesei, Viviana Life (Basel) Review Heart failure management has been repeatedly reviewed over time. This strategy has resulted in improved quality of life, especially in patients with heart failure with reduced ejection fraction (HFrEF). It is for this reason that new mechanisms involved in the development and progression of heart failure, along with specific therapies, have been identified. This review focuses on the most recent guidelines of therapeutic interventions, trials that explore novel therapies, and also new molecules that could improve prognosis of different HFrEF phenotypes. MDPI 2022-07-24 /pmc/articles/PMC9394280/ /pubmed/35892914 http://dx.doi.org/10.3390/life12081112 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Moloce, Maria-Angela
Costache, Irina-Iuliana
Nicolae, Ana
Onofrei Aursulesei, Viviana
Pharmacological Targets in Chronic Heart Failure with Reduced Ejection Fraction
title Pharmacological Targets in Chronic Heart Failure with Reduced Ejection Fraction
title_full Pharmacological Targets in Chronic Heart Failure with Reduced Ejection Fraction
title_fullStr Pharmacological Targets in Chronic Heart Failure with Reduced Ejection Fraction
title_full_unstemmed Pharmacological Targets in Chronic Heart Failure with Reduced Ejection Fraction
title_short Pharmacological Targets in Chronic Heart Failure with Reduced Ejection Fraction
title_sort pharmacological targets in chronic heart failure with reduced ejection fraction
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394280/
https://www.ncbi.nlm.nih.gov/pubmed/35892914
http://dx.doi.org/10.3390/life12081112
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AT onofreiaursuleseiviviana pharmacologicaltargetsinchronicheartfailurewithreducedejectionfraction

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