Activation of SIRT-1 Pathway by Nanoceria Sheds Light on Its Ameliorative Effect on Doxorubicin-Induced Cognitive Impairment (Chemobrain): Restraining Its Neuroinflammation, Synaptic Dysplasticity and Apoptosis

Chemo fog is one of the most serious health concerns encountered by cancer survivors receiving doxorubicin (DOX)-based chemotherapy. Oxidative stress, neuroinflammation, apoptosis and impairment of synaptic plasticity are regarded as the key factors implicated in DOX-induced cognitive impairment. Th...

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Detalles Bibliográficos
Autores principales: Taha, Medhat, Elazab, Sara T., Badawy, Alaa. M., Saati, Abdullah A., Qusty, Naeem F., Al-Kushi, Abdullah G., Sarhan, Anas, Osman, Amira, Farage, Amira E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394293/
https://www.ncbi.nlm.nih.gov/pubmed/35893742
http://dx.doi.org/10.3390/ph15080918

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