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Advances in the Diagnosis of Pancreatic Cystic Lesions
Pancreatic cystic lesions (PCLs) are a heterogenous group of lesions ranging from benign to malignant. There has been an increase in PCLs prevalence in recent years, mostly due to advances in imaging techniques, increased awareness of their existence and population aging. Reliable discrimination bet...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394320/ https://www.ncbi.nlm.nih.gov/pubmed/35892490 http://dx.doi.org/10.3390/diagnostics12081779 |
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author | Pușcașu, Claudia Irina Rimbaş, Mihai Mateescu, Radu Bogdan Larghi, Alberto Cauni, Victor |
author_facet | Pușcașu, Claudia Irina Rimbaş, Mihai Mateescu, Radu Bogdan Larghi, Alberto Cauni, Victor |
author_sort | Pușcașu, Claudia Irina |
collection | PubMed |
description | Pancreatic cystic lesions (PCLs) are a heterogenous group of lesions ranging from benign to malignant. There has been an increase in PCLs prevalence in recent years, mostly due to advances in imaging techniques, increased awareness of their existence and population aging. Reliable discrimination between neoplastic and non-neoplastic cystic lesions is paramount to ensuring adequate treatment and follow-up. Although conventional diagnostic techniques such as ultrasound (US), magnetic resonance imaging (MRI) and computer tomography (CT) can easily identify these lesions, assessing the risk of malignancy is limited. Endoscopic ultrasound (EUS) is superior to cross-sectional imaging in identifying potentially malignant lesions due to its high resolution and better imaging characteristics, and the advantage of allowing for cyst fluid sampling via fine-needle aspiration (FNA). More complex testing, such as cytological and histopathological analysis and biochemical and molecular testing of the aspirated fluid, can ensure an accurate diagnosis. |
format | Online Article Text |
id | pubmed-9394320 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-93943202022-08-23 Advances in the Diagnosis of Pancreatic Cystic Lesions Pușcașu, Claudia Irina Rimbaş, Mihai Mateescu, Radu Bogdan Larghi, Alberto Cauni, Victor Diagnostics (Basel) Review Pancreatic cystic lesions (PCLs) are a heterogenous group of lesions ranging from benign to malignant. There has been an increase in PCLs prevalence in recent years, mostly due to advances in imaging techniques, increased awareness of their existence and population aging. Reliable discrimination between neoplastic and non-neoplastic cystic lesions is paramount to ensuring adequate treatment and follow-up. Although conventional diagnostic techniques such as ultrasound (US), magnetic resonance imaging (MRI) and computer tomography (CT) can easily identify these lesions, assessing the risk of malignancy is limited. Endoscopic ultrasound (EUS) is superior to cross-sectional imaging in identifying potentially malignant lesions due to its high resolution and better imaging characteristics, and the advantage of allowing for cyst fluid sampling via fine-needle aspiration (FNA). More complex testing, such as cytological and histopathological analysis and biochemical and molecular testing of the aspirated fluid, can ensure an accurate diagnosis. MDPI 2022-07-22 /pmc/articles/PMC9394320/ /pubmed/35892490 http://dx.doi.org/10.3390/diagnostics12081779 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Pușcașu, Claudia Irina Rimbaş, Mihai Mateescu, Radu Bogdan Larghi, Alberto Cauni, Victor Advances in the Diagnosis of Pancreatic Cystic Lesions |
title | Advances in the Diagnosis of Pancreatic Cystic Lesions |
title_full | Advances in the Diagnosis of Pancreatic Cystic Lesions |
title_fullStr | Advances in the Diagnosis of Pancreatic Cystic Lesions |
title_full_unstemmed | Advances in the Diagnosis of Pancreatic Cystic Lesions |
title_short | Advances in the Diagnosis of Pancreatic Cystic Lesions |
title_sort | advances in the diagnosis of pancreatic cystic lesions |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394320/ https://www.ncbi.nlm.nih.gov/pubmed/35892490 http://dx.doi.org/10.3390/diagnostics12081779 |
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