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Advances in the Diagnosis of Pancreatic Cystic Lesions

Pancreatic cystic lesions (PCLs) are a heterogenous group of lesions ranging from benign to malignant. There has been an increase in PCLs prevalence in recent years, mostly due to advances in imaging techniques, increased awareness of their existence and population aging. Reliable discrimination bet...

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Detalles Bibliográficos
Autores principales: Pușcașu, Claudia Irina, Rimbaş, Mihai, Mateescu, Radu Bogdan, Larghi, Alberto, Cauni, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394320/
https://www.ncbi.nlm.nih.gov/pubmed/35892490
http://dx.doi.org/10.3390/diagnostics12081779
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author Pușcașu, Claudia Irina
Rimbaş, Mihai
Mateescu, Radu Bogdan
Larghi, Alberto
Cauni, Victor
author_facet Pușcașu, Claudia Irina
Rimbaş, Mihai
Mateescu, Radu Bogdan
Larghi, Alberto
Cauni, Victor
author_sort Pușcașu, Claudia Irina
collection PubMed
description Pancreatic cystic lesions (PCLs) are a heterogenous group of lesions ranging from benign to malignant. There has been an increase in PCLs prevalence in recent years, mostly due to advances in imaging techniques, increased awareness of their existence and population aging. Reliable discrimination between neoplastic and non-neoplastic cystic lesions is paramount to ensuring adequate treatment and follow-up. Although conventional diagnostic techniques such as ultrasound (US), magnetic resonance imaging (MRI) and computer tomography (CT) can easily identify these lesions, assessing the risk of malignancy is limited. Endoscopic ultrasound (EUS) is superior to cross-sectional imaging in identifying potentially malignant lesions due to its high resolution and better imaging characteristics, and the advantage of allowing for cyst fluid sampling via fine-needle aspiration (FNA). More complex testing, such as cytological and histopathological analysis and biochemical and molecular testing of the aspirated fluid, can ensure an accurate diagnosis.
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spelling pubmed-93943202022-08-23 Advances in the Diagnosis of Pancreatic Cystic Lesions Pușcașu, Claudia Irina Rimbaş, Mihai Mateescu, Radu Bogdan Larghi, Alberto Cauni, Victor Diagnostics (Basel) Review Pancreatic cystic lesions (PCLs) are a heterogenous group of lesions ranging from benign to malignant. There has been an increase in PCLs prevalence in recent years, mostly due to advances in imaging techniques, increased awareness of their existence and population aging. Reliable discrimination between neoplastic and non-neoplastic cystic lesions is paramount to ensuring adequate treatment and follow-up. Although conventional diagnostic techniques such as ultrasound (US), magnetic resonance imaging (MRI) and computer tomography (CT) can easily identify these lesions, assessing the risk of malignancy is limited. Endoscopic ultrasound (EUS) is superior to cross-sectional imaging in identifying potentially malignant lesions due to its high resolution and better imaging characteristics, and the advantage of allowing for cyst fluid sampling via fine-needle aspiration (FNA). More complex testing, such as cytological and histopathological analysis and biochemical and molecular testing of the aspirated fluid, can ensure an accurate diagnosis. MDPI 2022-07-22 /pmc/articles/PMC9394320/ /pubmed/35892490 http://dx.doi.org/10.3390/diagnostics12081779 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Pușcașu, Claudia Irina
Rimbaş, Mihai
Mateescu, Radu Bogdan
Larghi, Alberto
Cauni, Victor
Advances in the Diagnosis of Pancreatic Cystic Lesions
title Advances in the Diagnosis of Pancreatic Cystic Lesions
title_full Advances in the Diagnosis of Pancreatic Cystic Lesions
title_fullStr Advances in the Diagnosis of Pancreatic Cystic Lesions
title_full_unstemmed Advances in the Diagnosis of Pancreatic Cystic Lesions
title_short Advances in the Diagnosis of Pancreatic Cystic Lesions
title_sort advances in the diagnosis of pancreatic cystic lesions
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394320/
https://www.ncbi.nlm.nih.gov/pubmed/35892490
http://dx.doi.org/10.3390/diagnostics12081779
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