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Modulation of Multiple Gene Clusters’ Expression by the PAS-LuxR Transcriptional Regulator PteF
PAS-LuxR transcriptional regulators are conserved proteins governing polyene antifungal biosynthesis. PteF is the regulator of filipin biosynthesis from Streptomyces avermitilis. Its mutation drastically abates filipin, but also oligomycin production, a macrolide ATP-synthase inhibitor, and delays s...
Autores principales: | Vicente, Cláudia M., Payero, Tamara D., Rodríguez-García, Antonio, Barreales, Eva G., de Pedro, Antonio, Santos-Beneit, Fernando, Aparicio, Jesús F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394381/ https://www.ncbi.nlm.nih.gov/pubmed/35892384 http://dx.doi.org/10.3390/antibiotics11080994 |
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