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Modulation of Multiple Gene Clusters’ Expression by the PAS-LuxR Transcriptional Regulator PteF

PAS-LuxR transcriptional regulators are conserved proteins governing polyene antifungal biosynthesis. PteF is the regulator of filipin biosynthesis from Streptomyces avermitilis. Its mutation drastically abates filipin, but also oligomycin production, a macrolide ATP-synthase inhibitor, and delays s...

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Detalles Bibliográficos
Autores principales: Vicente, Cláudia M., Payero, Tamara D., Rodríguez-García, Antonio, Barreales, Eva G., de Pedro, Antonio, Santos-Beneit, Fernando, Aparicio, Jesús F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394381/
https://www.ncbi.nlm.nih.gov/pubmed/35892384
http://dx.doi.org/10.3390/antibiotics11080994

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