Single-Cell Atlas of Lineage States, Tumor Microenvironment, and Subtype-Specific Expression Programs in Gastric Cancer

Gastric cancer heterogeneity represents a barrier to disease management. We generated a comprehensive single-cell atlas of gastric cancer (>200,000 cells) comprising 48 samples from 31 patients across clinical stages and histologic subtypes. We identified 34 distinct cell-lineage states including...

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Detalles Bibliográficos
Autores principales: Kumar, Vikrant, Ramnarayanan, Kalpana, Sundar, Raghav, Padmanabhan, Nisha, Srivastava, Supriya, Koiwa, Mayu, Yasuda, Tadahito, Koh, Vivien, Huang, Kie Kyon, Tay, Su Ting, Ho, Shamaine Wei Ting, Tan, Angie Lay Keng, Ishimoto, Takatsugu, Kim, Guowei, Shabbir, Asim, Chen, Qingfeng, Zhang, Biyan, Xu, Shengli, Lam, Kong-Peng, Lum, Huey Yew Jeffrey, Teh, Ming, Yong, Wei Peng, So, Jimmy Bok Yan, Tan, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394383/
https://www.ncbi.nlm.nih.gov/pubmed/34642171
http://dx.doi.org/10.1158/2159-8290.CD-21-0683

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