Comprehensive Genomic Profiling of Neuroendocrine Carcinomas of the Gastrointestinal System

The neuroendocrine carcinoma of the gastrointestinal system (GIS-NEC) is a rare but highly malignant neoplasm. We analyzed 115 cases using whole-genome/exome sequencing, transcriptome sequencing, DNA methylation assays, and/or ATAC-seq and found GIS-NECs to be genetically distinct from neuroendocrin...

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Detalles Bibliográficos
Autores principales: Yachida, Shinichi, Totoki, Yasushi, Noë, Michaël, Nakatani, Yoichiro, Horie, Masafumi, Kawasaki, Kenta, Nakamura, Hiromi, Saito-Adachi, Mihoko, Suzuki, Masami, Takai, Erina, Hama, Natsuko, Higuchi, Ryota, Hirono, Seiko, Shiba, Satoshi, Kato, Mamoru, Furukawa, Eisaku, Arai, Yasuhito, Rokutan, Hirofumi, Hashimoto, Taiki, Mitsunaga, Shuichi, Kanda, Mitsuro, Tanaka, Hidenori, Takata, So, Shimomura, Ayaka, Oshima, Minoru, Hackeng, Wenzel M., Okumura, Tomoyuki, Okano, Keiichi, Yamamoto, Masakazu, Yamaue, Hiroki, Morizane, Chigusa, Arihiro, Koji, Furukawa, Toru, Sato, Toshiro, Kiyono, Tohru, Brosens, Lodewijk A.A., Wood, Laura D., Hruban, Ralph H., Shibata, Tatsuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394397/
https://www.ncbi.nlm.nih.gov/pubmed/34880079
http://dx.doi.org/10.1158/2159-8290.CD-21-0669

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