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NMR and Metabolomics—A Roadmap for the Future
Metabolomics investigates global metabolic alterations associated with chemical, biological, physiological, or pathological processes. These metabolic changes are measured with various analytical platforms including liquid chromatography-mass spectrometry (LC-MS), gas chromatography-mass spectrometr...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394421/ https://www.ncbi.nlm.nih.gov/pubmed/35893244 http://dx.doi.org/10.3390/metabo12080678 |
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author | Wishart, David S. Cheng, Leo L. Copié, Valérie Edison, Arthur S. Eghbalnia, Hamid R. Hoch, Jeffrey C. Gouveia, Goncalo J. Pathmasiri, Wimal Powers, Robert Schock, Tracey B. Sumner, Lloyd W. Uchimiya, Mario |
author_facet | Wishart, David S. Cheng, Leo L. Copié, Valérie Edison, Arthur S. Eghbalnia, Hamid R. Hoch, Jeffrey C. Gouveia, Goncalo J. Pathmasiri, Wimal Powers, Robert Schock, Tracey B. Sumner, Lloyd W. Uchimiya, Mario |
author_sort | Wishart, David S. |
collection | PubMed |
description | Metabolomics investigates global metabolic alterations associated with chemical, biological, physiological, or pathological processes. These metabolic changes are measured with various analytical platforms including liquid chromatography-mass spectrometry (LC-MS), gas chromatography-mass spectrometry (GC-MS) and nuclear magnetic resonance spectroscopy (NMR). While LC-MS methods are becoming increasingly popular in the field of metabolomics (accounting for more than 70% of published metabolomics studies to date), there are considerable benefits and advantages to NMR-based methods for metabolomic studies. In fact, according to PubMed, more than 926 papers on NMR-based metabolomics were published in 2021—the most ever published in a given year. This suggests that NMR-based metabolomics continues to grow and has plenty to offer to the scientific community. This perspective outlines the growing applications of NMR in metabolomics, highlights several recent advances in NMR technologies for metabolomics, and provides a roadmap for future advancements. |
format | Online Article Text |
id | pubmed-9394421 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-93944212022-08-23 NMR and Metabolomics—A Roadmap for the Future Wishart, David S. Cheng, Leo L. Copié, Valérie Edison, Arthur S. Eghbalnia, Hamid R. Hoch, Jeffrey C. Gouveia, Goncalo J. Pathmasiri, Wimal Powers, Robert Schock, Tracey B. Sumner, Lloyd W. Uchimiya, Mario Metabolites Review Metabolomics investigates global metabolic alterations associated with chemical, biological, physiological, or pathological processes. These metabolic changes are measured with various analytical platforms including liquid chromatography-mass spectrometry (LC-MS), gas chromatography-mass spectrometry (GC-MS) and nuclear magnetic resonance spectroscopy (NMR). While LC-MS methods are becoming increasingly popular in the field of metabolomics (accounting for more than 70% of published metabolomics studies to date), there are considerable benefits and advantages to NMR-based methods for metabolomic studies. In fact, according to PubMed, more than 926 papers on NMR-based metabolomics were published in 2021—the most ever published in a given year. This suggests that NMR-based metabolomics continues to grow and has plenty to offer to the scientific community. This perspective outlines the growing applications of NMR in metabolomics, highlights several recent advances in NMR technologies for metabolomics, and provides a roadmap for future advancements. MDPI 2022-07-23 /pmc/articles/PMC9394421/ /pubmed/35893244 http://dx.doi.org/10.3390/metabo12080678 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Wishart, David S. Cheng, Leo L. Copié, Valérie Edison, Arthur S. Eghbalnia, Hamid R. Hoch, Jeffrey C. Gouveia, Goncalo J. Pathmasiri, Wimal Powers, Robert Schock, Tracey B. Sumner, Lloyd W. Uchimiya, Mario NMR and Metabolomics—A Roadmap for the Future |
title | NMR and Metabolomics—A Roadmap for the Future |
title_full | NMR and Metabolomics—A Roadmap for the Future |
title_fullStr | NMR and Metabolomics—A Roadmap for the Future |
title_full_unstemmed | NMR and Metabolomics—A Roadmap for the Future |
title_short | NMR and Metabolomics—A Roadmap for the Future |
title_sort | nmr and metabolomics—a roadmap for the future |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394421/ https://www.ncbi.nlm.nih.gov/pubmed/35893244 http://dx.doi.org/10.3390/metabo12080678 |
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