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Mitochondrial Ca(2+) Uptake Drives Endothelial Injury By Radiation Therapy

Radiation therapy strongly increases the risk of atherosclerotic vascular disease, such as carotid stenosis. Radiation induces DNA damage, in particular in mitochondria, but the upstream and downstream signaling events are poorly understood. The objective of this study was to define such mechanisms....

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Detalles Bibliográficos
Autores principales: Ait-Aissa, Karima, Koval, Olha M., Lindsey, Nathanial R., Grumbach, Isabella M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394506/
https://www.ncbi.nlm.nih.gov/pubmed/35899616
http://dx.doi.org/10.1161/ATVBAHA.122.317869