Genome sequence of the aurodox-producing bacterium Streptomyces goldiniensis ATCC 21386

We report the genome sequence of Streptomyces goldiniensis ATCC 21386, a strain which produces the anti-bacterial and anti-virulence polyketide, aurodox. The genome of S. goldiniensis ATCC 21386 was sequenced using a multiplatform hybrid approach, revealing a linear genome of ~10 Mbp with a G+C cont...

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Autores principales: McHugh, Rebecca E., Munnoch, John T., Roe, Andrew J., Hoskisson, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394534/
https://www.ncbi.nlm.nih.gov/pubmed/36003359
http://dx.doi.org/10.1099/acmi.0.000358
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author McHugh, Rebecca E.
Munnoch, John T.
Roe, Andrew J.
Hoskisson, Paul A.
author_facet McHugh, Rebecca E.
Munnoch, John T.
Roe, Andrew J.
Hoskisson, Paul A.
author_sort McHugh, Rebecca E.
collection PubMed
description We report the genome sequence of Streptomyces goldiniensis ATCC 21386, a strain which produces the anti-bacterial and anti-virulence polyketide, aurodox. The genome of S. goldiniensis ATCC 21386 was sequenced using a multiplatform hybrid approach, revealing a linear genome of ~10 Mbp with a G+C content of 71%. The genome sequence revealed 36 putative biosynthetic gene clusters (BGCs), including a large region of 271 Kbp that was rich in biosynthetic capability. The genome sequence is deposited in DDBJ/EMBL/GenBank with the accession number PRJNA602141.
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spelling pubmed-93945342022-08-23 Genome sequence of the aurodox-producing bacterium Streptomyces goldiniensis ATCC 21386 McHugh, Rebecca E. Munnoch, John T. Roe, Andrew J. Hoskisson, Paul A. Access Microbiol Research Articles We report the genome sequence of Streptomyces goldiniensis ATCC 21386, a strain which produces the anti-bacterial and anti-virulence polyketide, aurodox. The genome of S. goldiniensis ATCC 21386 was sequenced using a multiplatform hybrid approach, revealing a linear genome of ~10 Mbp with a G+C content of 71%. The genome sequence revealed 36 putative biosynthetic gene clusters (BGCs), including a large region of 271 Kbp that was rich in biosynthetic capability. The genome sequence is deposited in DDBJ/EMBL/GenBank with the accession number PRJNA602141. Microbiology Society 2022-08-19 /pmc/articles/PMC9394534/ /pubmed/36003359 http://dx.doi.org/10.1099/acmi.0.000358 Text en © 2022 The Authors https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License. This article was made open access via a Publish and Read agreement between the Microbiology Society and the corresponding author’s institution.
spellingShingle Research Articles
McHugh, Rebecca E.
Munnoch, John T.
Roe, Andrew J.
Hoskisson, Paul A.
Genome sequence of the aurodox-producing bacterium Streptomyces goldiniensis ATCC 21386
title Genome sequence of the aurodox-producing bacterium Streptomyces goldiniensis ATCC 21386
title_full Genome sequence of the aurodox-producing bacterium Streptomyces goldiniensis ATCC 21386
title_fullStr Genome sequence of the aurodox-producing bacterium Streptomyces goldiniensis ATCC 21386
title_full_unstemmed Genome sequence of the aurodox-producing bacterium Streptomyces goldiniensis ATCC 21386
title_short Genome sequence of the aurodox-producing bacterium Streptomyces goldiniensis ATCC 21386
title_sort genome sequence of the aurodox-producing bacterium streptomyces goldiniensis atcc 21386
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394534/
https://www.ncbi.nlm.nih.gov/pubmed/36003359
http://dx.doi.org/10.1099/acmi.0.000358
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