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Physical exercise is effective for neuropsychiatric symptoms in Alzheimer's disease: a systematic review

BACKGROUND: Neuropsychiatric symptoms are disorders frequently seen in Alzheimer's disease. These symptoms contribute to reduction of brain reserve capacity and, in addition, they present unfavorable implications, such as: poor prognosis for the disease, increased functional decline, increased...

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Autores principales: Mendonça, Dayanne Christine Borges, Fernandes, Denise Rodrigues, Hernandez, Salma Soleman, Soares, Fernando Diákson Gontijo, de Figueiredo, Karina, Coelho, Flávia Gomes de Melo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academia Brasileira de Neurologia - ABNEURO 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394554/
https://www.ncbi.nlm.nih.gov/pubmed/34161531
http://dx.doi.org/10.1590/0004-282X-ANP-2020-0284
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author Mendonça, Dayanne Christine Borges
Fernandes, Denise Rodrigues
Hernandez, Salma Soleman
Soares, Fernando Diákson Gontijo
de Figueiredo, Karina
Coelho, Flávia Gomes de Melo
author_facet Mendonça, Dayanne Christine Borges
Fernandes, Denise Rodrigues
Hernandez, Salma Soleman
Soares, Fernando Diákson Gontijo
de Figueiredo, Karina
Coelho, Flávia Gomes de Melo
author_sort Mendonça, Dayanne Christine Borges
collection PubMed
description BACKGROUND: Neuropsychiatric symptoms are disorders frequently seen in Alzheimer's disease. These symptoms contribute to reduction of brain reserve capacity and, in addition, they present unfavorable implications, such as: poor prognosis for the disease, increased functional decline, increased burden on the caregiver and institutionalization. This scenario makes neuropsychiatric symptoms one of the biggest problems in Alzheimer's disease, and gives rise to a need for treatments focused on improving these symptoms. Sow progress in drug trials has led to interest in exploring non-pharmacological measures for improving the neuropsychiatric symptoms of Alzheimer's disease, such as physical exercise. OBJECTIVE: To ascertain the effect of exercise on the neuropsychiatric symptoms of Alzheimer's disease and its implications. METHODS: This was a systematic review of effective longitudinal research, conducted by searching for articles in the PubMed, Web of Science, CINAHL and Scopus electronic databases, from 2009 to 2019. Studies in which the sample consisted of elderly people aged 65 years old or over with a diagnosis of Alzheimer's disease were included. Initially 334 articles were identified. After exclusions, 21 articles remained to be read in full. From these, five articles fitted the eligibility criteria, and a further two articles were added through manual searches in the references of the articles found. RESULTS: Out of the seven articles analyzed in this review, five studies revealed that physical exercise had a positive effect on the neuropsychiatric symptoms of Alzheimer's disease. CONCLUSION: This systematic review indicated that physical exercise is a favorable non-pharmacological means for attenuating the neuropsychiatric symptoms of elderly people with Alzheimer's disease, with special attention to aerobic exercises.
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spelling pubmed-93945542022-12-08 Physical exercise is effective for neuropsychiatric symptoms in Alzheimer's disease: a systematic review Mendonça, Dayanne Christine Borges Fernandes, Denise Rodrigues Hernandez, Salma Soleman Soares, Fernando Diákson Gontijo de Figueiredo, Karina Coelho, Flávia Gomes de Melo Arq Neuropsiquiatr View and Review BACKGROUND: Neuropsychiatric symptoms are disorders frequently seen in Alzheimer's disease. These symptoms contribute to reduction of brain reserve capacity and, in addition, they present unfavorable implications, such as: poor prognosis for the disease, increased functional decline, increased burden on the caregiver and institutionalization. This scenario makes neuropsychiatric symptoms one of the biggest problems in Alzheimer's disease, and gives rise to a need for treatments focused on improving these symptoms. Sow progress in drug trials has led to interest in exploring non-pharmacological measures for improving the neuropsychiatric symptoms of Alzheimer's disease, such as physical exercise. OBJECTIVE: To ascertain the effect of exercise on the neuropsychiatric symptoms of Alzheimer's disease and its implications. METHODS: This was a systematic review of effective longitudinal research, conducted by searching for articles in the PubMed, Web of Science, CINAHL and Scopus electronic databases, from 2009 to 2019. Studies in which the sample consisted of elderly people aged 65 years old or over with a diagnosis of Alzheimer's disease were included. Initially 334 articles were identified. After exclusions, 21 articles remained to be read in full. From these, five articles fitted the eligibility criteria, and a further two articles were added through manual searches in the references of the articles found. RESULTS: Out of the seven articles analyzed in this review, five studies revealed that physical exercise had a positive effect on the neuropsychiatric symptoms of Alzheimer's disease. CONCLUSION: This systematic review indicated that physical exercise is a favorable non-pharmacological means for attenuating the neuropsychiatric symptoms of elderly people with Alzheimer's disease, with special attention to aerobic exercises. Academia Brasileira de Neurologia - ABNEURO 2021-05-01 /pmc/articles/PMC9394554/ /pubmed/34161531 http://dx.doi.org/10.1590/0004-282X-ANP-2020-0284 Text en https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle View and Review
Mendonça, Dayanne Christine Borges
Fernandes, Denise Rodrigues
Hernandez, Salma Soleman
Soares, Fernando Diákson Gontijo
de Figueiredo, Karina
Coelho, Flávia Gomes de Melo
Physical exercise is effective for neuropsychiatric symptoms in Alzheimer's disease: a systematic review
title Physical exercise is effective for neuropsychiatric symptoms in Alzheimer's disease: a systematic review
title_full Physical exercise is effective for neuropsychiatric symptoms in Alzheimer's disease: a systematic review
title_fullStr Physical exercise is effective for neuropsychiatric symptoms in Alzheimer's disease: a systematic review
title_full_unstemmed Physical exercise is effective for neuropsychiatric symptoms in Alzheimer's disease: a systematic review
title_short Physical exercise is effective for neuropsychiatric symptoms in Alzheimer's disease: a systematic review
title_sort physical exercise is effective for neuropsychiatric symptoms in alzheimer's disease: a systematic review
topic View and Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394554/
https://www.ncbi.nlm.nih.gov/pubmed/34161531
http://dx.doi.org/10.1590/0004-282X-ANP-2020-0284
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