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Nonabsorbable intrasellar stent placement for recurrent Rathke cleft cyst: illustrative case

BACKGROUND: Rathke cleft cyst (RCC) has a recurrence rate of 10% to 22%, and preventing recurrence is challenging. For patients who experience persistent recurrence of RCC, placement of steroid-eluting bioabsorbable intrasellar stents has been rarely described. However, recurrences are often delayed...

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Autores principales: Ellens, Nathaniel R., Miller, Matthew C., Shafiq, Ismat, Williams, Zoe R., Vates, G. Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association of Neurological Surgeons 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394677/
https://www.ncbi.nlm.nih.gov/pubmed/36046794
http://dx.doi.org/10.3171/CASE2117
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author Ellens, Nathaniel R.
Miller, Matthew C.
Shafiq, Ismat
Williams, Zoe R.
Vates, G. Edward
author_facet Ellens, Nathaniel R.
Miller, Matthew C.
Shafiq, Ismat
Williams, Zoe R.
Vates, G. Edward
author_sort Ellens, Nathaniel R.
collection PubMed
description BACKGROUND: Rathke cleft cyst (RCC) has a recurrence rate of 10% to 22%, and preventing recurrence is challenging. For patients who experience persistent recurrence of RCC, placement of steroid-eluting bioabsorbable intrasellar stents has been rarely described. However, recurrences are often delayed, suggesting that dissolvable stents may not be successful long-term. The release of steroids in close proximity to the pituitary gland may also unintentionally influence the hypothalamic-adrenal-pituitary axis. OBSERVATIONS: The authors present a case of a 66-year-old woman with a persistently recurrent RCC who underwent drainage of her cyst with placement of a nonabsorbable intrasellar stent in the form of a tympanostomy tube. After repeat transsphenoidal drainage of her cyst, a tympanostomy T-tube was placed to stent open the dural aperture. Postoperatively, the patient’s condition showed improvement clinically and radiographically. LESSONS: Placement of an intrasellar stent for recurrent RCC has rarely been described. Steroid-eluting bioabsorbable stents may dissolve before RCC recurrence and may have an unintentional effect on the hypothalamic-pituitary-adrenal axis. The authors present the first case of nonabsorbable stent placement in the form of a tympanostomy tube for recurrence of RCC. Additional studies and longer follow-up are necessary to evaluate the long-term efficacy of both absorbable and nonabsorbable stent placement.
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spelling pubmed-93946772022-08-30 Nonabsorbable intrasellar stent placement for recurrent Rathke cleft cyst: illustrative case Ellens, Nathaniel R. Miller, Matthew C. Shafiq, Ismat Williams, Zoe R. Vates, G. Edward J Neurosurg Case Lessons Case Report BACKGROUND: Rathke cleft cyst (RCC) has a recurrence rate of 10% to 22%, and preventing recurrence is challenging. For patients who experience persistent recurrence of RCC, placement of steroid-eluting bioabsorbable intrasellar stents has been rarely described. However, recurrences are often delayed, suggesting that dissolvable stents may not be successful long-term. The release of steroids in close proximity to the pituitary gland may also unintentionally influence the hypothalamic-adrenal-pituitary axis. OBSERVATIONS: The authors present a case of a 66-year-old woman with a persistently recurrent RCC who underwent drainage of her cyst with placement of a nonabsorbable intrasellar stent in the form of a tympanostomy tube. After repeat transsphenoidal drainage of her cyst, a tympanostomy T-tube was placed to stent open the dural aperture. Postoperatively, the patient’s condition showed improvement clinically and radiographically. LESSONS: Placement of an intrasellar stent for recurrent RCC has rarely been described. Steroid-eluting bioabsorbable stents may dissolve before RCC recurrence and may have an unintentional effect on the hypothalamic-pituitary-adrenal axis. The authors present the first case of nonabsorbable stent placement in the form of a tympanostomy tube for recurrence of RCC. Additional studies and longer follow-up are necessary to evaluate the long-term efficacy of both absorbable and nonabsorbable stent placement. American Association of Neurological Surgeons 2021-04-12 /pmc/articles/PMC9394677/ /pubmed/36046794 http://dx.doi.org/10.3171/CASE2117 Text en © 2021 The authors https://creativecommons.org/licenses/by-nc-nd/4.0/CC BY-NC-ND 4.0 (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ).
spellingShingle Case Report
Ellens, Nathaniel R.
Miller, Matthew C.
Shafiq, Ismat
Williams, Zoe R.
Vates, G. Edward
Nonabsorbable intrasellar stent placement for recurrent Rathke cleft cyst: illustrative case
title Nonabsorbable intrasellar stent placement for recurrent Rathke cleft cyst: illustrative case
title_full Nonabsorbable intrasellar stent placement for recurrent Rathke cleft cyst: illustrative case
title_fullStr Nonabsorbable intrasellar stent placement for recurrent Rathke cleft cyst: illustrative case
title_full_unstemmed Nonabsorbable intrasellar stent placement for recurrent Rathke cleft cyst: illustrative case
title_short Nonabsorbable intrasellar stent placement for recurrent Rathke cleft cyst: illustrative case
title_sort nonabsorbable intrasellar stent placement for recurrent rathke cleft cyst: illustrative case
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394677/
https://www.ncbi.nlm.nih.gov/pubmed/36046794
http://dx.doi.org/10.3171/CASE2117
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