Afucosylated IgG responses in humans – structural clues to the regulation of humoral immunity

Healthy immune responses require efficient protection without excessive inflammation. Recent discoveries on the degree of fucosylation of a human N-linked glycan at a conserved site in the immunoglobulin IgG-Fc domain might add an additional regulatory layer to adaptive humoral immunity. Specificall...

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Detalles Bibliográficos
Autores principales: Oosterhoff, Janita J., Larsen, Mads Delbo, van der Schoot, C. Ellen, Vidarsson, Gestur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Ltd. 2022
Materias:
Opinion
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395167/
https://www.ncbi.nlm.nih.gov/pubmed/36008258
http://dx.doi.org/10.1016/j.it.2022.08.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395167/
https://www.ncbi.nlm.nih.gov/pubmed/36008258
http://dx.doi.org/10.1016/j.it.2022.08.001

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