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Afucosylated IgG responses in humans – structural clues to the regulation of humoral immunity
Healthy immune responses require efficient protection without excessive inflammation. Recent discoveries on the degree of fucosylation of a human N-linked glycan at a conserved site in the immunoglobulin IgG-Fc domain might add an additional regulatory layer to adaptive humoral immunity. Specificall...
Autores principales: | Oosterhoff, Janita J., Larsen, Mads Delbo, van der Schoot, C. Ellen, Vidarsson, Gestur |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Authors. Published by Elsevier Ltd.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395167/ https://www.ncbi.nlm.nih.gov/pubmed/36008258 http://dx.doi.org/10.1016/j.it.2022.08.001 |
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